ArticleCaries research2025
Validity and Reliability of Intraoral Optical Coherence Tomography and Bitewing Radiography for Detecting Approximal Carious Lesions.
Article in Caries research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Depolarization-Based Multimodal Optical Imaging of Carious Lesions.Journal of biophotonics · 2026Article
- Artificial intelligence for dental caries diagnosis: translating algorithms to clinical practice.Frontiers in medicine · 2026Review
- 3D Evaluation of material-dependent volumetric and interfacial changes in CAD/CAM partial crowns: a semi-automated micro-CT approach.Frontiers in dental medicine · 2026Article
- Bitewing Radiographs in Proximal Caries Diagnostics and Restorative Treatment of Adults: A Retrospective Study of Electronic Health Records.Caries research · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThis in vitro study evaluated the validity and reliability of spectral-domain optical coherence tomography (SD-OCT) to detect approximal carious lesions compared to bitewing radiography.
methodsForty extracted human premolars and molars with fifty-four unrestored approximal surfaces (ICDAS ll score 0-3) were mounted in a patient-equivalent simulator and imaged by digital radiography (DR) and the prototype of an intraoral OCT probe. The lesion status of the tooth surfaces was validated histologically and by microtomography (µCT). Five calibrated raters with low to high level of clinical expertise analyzed the DR and OCT images at intervals of 2-4 weeks each. Intra- and interrater agreement (weighted Cohen's kappa κ, Fleiss' kappa), sensitivity, and specificity were calculated.
resultsThe sensitivity of OCT (0.66-0.91) was higher than that of DR (0.46-0.82), as was the specificity (OCT: 0.67-0.92; DR: 0.33-0.58). Intrarater agreement with OCT was moderate to substantial (κ: 0.53-0.77; p < 0.001) and fair to substantial for DR (κ: 0.36-0.78; p < 0.05). The DR interpersonal agreement ranged from slight to substantial (κ: 0.1-0.74, Fleiss' κ: 0.23/0.24; p < 0.001) toward fair to substantial with OCT (κ: 0.27-0.62; Fleiss' κ: 0.23/0.18; p < 0.001). Agreement between histology and µCT was almost perfect (κ: 0.82; p < 0.001).
conclusionsIn a clinically oriented simulation, OCT was more sensitive in detecting early approximal carious lesions than DR without impairing specificity or reproducibility. Clinical studies will have to show whether OCT can confirm these promising results.
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