Evidence map›Paper›PMID 39999808›Full record

ArticleActa cytologica2025

Cytological Diagnosis by Fine-Needle Aspiration or Core Biopsy with Touch Preparation for Renal Cystic or Solid Lesions: A Single-Center Clinicopathological Analysis.

Jiayan Liu, Changwei Yang, Xiaohui Wu, Li Yang, Hong Xu

Abstract read
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Article in Acta cytologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jiayan LiuDepartment of Pathology, State Key Laboratory of Cancer Biology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
Changwei YangDepartment of Emergency Medicine, Xi'an Honghui Hospital, Xi'an, China.
Xiaohui WuClinical Medical School, Xi'an Medical University, Xi'an, China.
Li YangDepartment of Pathology, State Key Laboratory of Cancer Biology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
Hong XuDepartment of Pathology, State Key Laboratory of Cancer Biology, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA retrospective study analyzed real-life data from a single-center cohort of renal fine-needle aspiration (FNA) and core biopsy (CB) with touch preparation (TP) procedures over an 18-year period and aimed to provide a comprehensive overview of the evaluation of cytological diagnostic performance, challenges, and accuracy concerning renal cystic, solid, and mixed cystic-solid lesions.

methodsAll percutaneous ultrasound-guided FNA and CT-guided CB with TP performed at our institution from 2006 to 2024 were identified.

resultsA total of 89 renal cytology procedures were performed during the study period. Sixty-two (69.7%) lesions displayed cystic radiological features, 20 (22.5%) lesions presented solid mass, and only 7 (7.8%) lesions exhibited mixed cystic-solid radiological features. Of the procedures performed, seventy-five (84.3%) were ultrasound-guided FNA biopsies, while 14 (15.7%) were CT-guided CB with TP. Of the 62 renal cystic lesions, 54 (87.1%) were simple renal cysts. Twelve (60%) in 20 solid lesions were malignant, mainly involving clear cell renal cell carcinoma (RCC), urothelial carcinoma, and collecting duct carcinoma. Cytological diagnoses of renal mixed cystic-solid lesions mainly involved tuberculosis and clear cell RCC. However, only 22 cases had corresponding histopathological specimens available for comparison. The concordance rate between cytological diagnoses and surgical pathology specimens for cystic, solid, and mixed cystic-solid renal lesions was 100%, 92.3%, and 80%, respectively.

conclusionIn our series, FNA or CB with TP demonstrates significant diagnostic utility in the evaluation of renal lesions. The diagnostic accuracy of FNA cytology for renal lesions has been enhanced through the application of immunocytochemical staining on cell blocks.

Indexed as

Carcinoma, Renal CellKidneyKidney Diseases, CysticKidney NeoplasmsAdultAgedAged, 80 and overBiopsy, Fine-NeedleBiopsy, Large-Core NeedleFemaleHumansImage-Guided BiopsyMaleMiddle AgedReproducibility of ResultsRetrospective StudiesCore biopsiesCytologyFine-needle aspirationRenal lesionsTouch preparation

Identifiers

PMID39999808
PMCPMC12052385

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.