Evidence map›Paper›PMID 39999410›Full record

ArticleHealth physics2025

Dosimetry Testing for a New In Vivo X-ray Fluorescence Measurement System.

Chandler J Burgos, Daniel E Read, Thomas R Grier, Maruf Khan, Marc G Weisskopf, Kathryn M Taylor, Aaron J Specht

Abstract read
In one paragraph

Article in Health physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chandler J BurgosPurdue University, School of Health Sciences, West Lafayette, IN 47906.
Daniel E ReadPurdue University, School of Health Sciences, West Lafayette, IN 47906.
Thomas R GrierPurdue University, School of Health Sciences, West Lafayette, IN 47906.
Maruf KhanPurdue University, School of Health Sciences, West Lafayette, IN 47906.
Marc G WeisskopfHarvard T.H. Chan School of Public Health, Boston, MA 02115.
Kathryn M TaylorUnited States Army Research Institute of Environmental Medicine, Natick, MA 01760.
Aaron J SpechtPurdue University, School of Health Sciences, West Lafayette, IN 47906.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
NIEHS NIH HHS P30 ES000002NIOSH CDC HHS K01 OH011648NIOSH CDC HHS K01 OH012528
6 · The paper itself

Abstract

abstractLead exposure poses severe health risks to individuals, impacting cognitive function, growth, learning, and behavior. Current lead detection methods, primarily blood testing and x-ray fluorescence (XRF) of bone, have limitations. This study introduces a novel in vivo XRF measurement system using K-shell energies of lead, addressing limitations of previous methods. The study aimed to characterize beam directionality, subject radiation dose, and operator occupational exposure. Using a high-energy x-ray tube and room-temperature detectors, various parameters were assessed with bone and tissue phantoms. Dose measurements were taken by altering voltage, current, and shielding. Scatter and spatial measurements highlighted increased scatter with bone and tissue presence, emphasizing the safest positions for bystanders and operators. Results exhibited expected dose rate changes with varying parameters, showcasing the impact of bone and tissue on scatter radiation. The system's total body effective dose (with an 8-mm molybdenum shielding indicating minimal risk compared to established public dose limits) for an adult was 1.94 μSv; for a child aged 10 y, it was 3.28 μSv. This system demonstrates promising capabilities for lead exposure monitoring, offering negligible occupational exposure and minimal risk to individuals being scanned. Its safety and efficacy position it as a valuable tool in assessing lead exposure, potentially improving preventive measures.

Indexed as

RadiometrySpectrometry, X-Ray EmissionAdultBone and BonesChildHumansLeadOccupational ExposurePhantoms, ImagingRadiation DosageRadiation ExposureScattering, RadiationX-RaysLead

Identifiers

PMID39999410
PMCPMC11864586

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.