Evidence map›Paper›PMID 39999339›Full record

ArticleACS synthetic biology2025

Heterologous Expression of a Cryptic BGC from

Maximilian Hohmann, Denis Iliasov, Martin Larralde, Widya Johannes, Klaus-Peter Janßen, Georg Zeller, Thorsten Mascher, Tobias A M Gulder

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS synthetic biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maximilian HohmannChair of Technical Biochemistry, TUD Dresden University of Technology, Bergstraße 66, 01069 Dresden, Germany.
Denis IliasovGeneral Microbiology, TUD Dresden University of Technology, Zellescher Weg 20b, 01217 Dresden, Germany.
Martin LarraldeLeiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center, 2333 ZA Leiden, Netherlands.ORCID 0000-0002-3947-4444
Widya JohannesDepartment of Surgery, School of Medicine and Health, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, Germany.
Klaus-Peter JanßenDepartment of Surgery, School of Medicine and Health, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, Germany.
Georg ZellerLeiden University Center for Infectious Diseases (LUCID) and Center for Microbiome Analyses and Therapeutics (CMAT), Leiden University Medical Center, 2333 ZA Leiden, Netherlands.
Thorsten MascherGeneral Microbiology, TUD Dresden University of Technology, Zellescher Weg 20b, 01217 Dresden, Germany.ORCID 0000-0002-6300-5541
Tobias A M GulderChair of Technical Biochemistry, TUD Dresden University of Technology, Bergstraße 66, 01069 Dresden, Germany.ORCID 0000-0001-6013-3161

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human health is greatly influenced by the gut microbiota and microbiota imbalance can lead to the development of diseases. It is widely acknowledged that the interaction of bacteria within competitive ecosystems is influenced by their specialized metabolites, which act, e.g., as antibacterials or siderophores. However, our understanding of the occurrence and impact of such natural products in the human gut microbiome remains very limited. As arylthiazole siderophores are an emerging family of growth-promoting molecules in pathogenic bacteria, we analyzed a metagenomic data set from the human microbiome and thereby identified the

Indexed as

Anti-Bacterial AgentsBacteroidetesThiazolesGastrointestinal MicrobiomeHumansAnti-Bacterial AgentsThiazolesantibioticsBilophila sp.bilothiazolesDiPaCgut mircrobiomenatural products

Identifiers

PMID39999339
PMCPMC11934131

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.