Evidence map›Paper›PMID 39998901›Full record

ArticleJornal brasileiro de nefrologia

Secondary hyperparathyroidism due to chronic kidney disease and access to clinical treatment and parathyroidectomy in Brazil: a nationwide survey.

Lauter Eston Pelepenko, Marcelo Giacomini Louça, Tarcísio Fausto, Sergio Gardano Elias Bucharles, Melani Ribeiro Custódio, Leandro Lucca Junior, Fellype de Carvalho Barreto, Aluízio Barbosa Carvalho, Vanda Jorgetti, José Andrade Moura Neto and 1 more

Abstract read
In one paragraph

Article in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Brazilian Dialysis Survey 2024.Jornal brasileiro de nefrologia · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lauter Eston PelepenkoUniversidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas, Laboratório para o Estudo Mineral e Ósseo em Nefrologia (LEMON), Campinas, SP, Brazil.ORCID http://orcid.org/0000-0002-8365-8267
Marcelo Giacomini LouçaUniversidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas, Departamento de Clínica Médica (Nefrologia), Campinas, SP, Brazil.ORCID http://orcid.org/0009-0009-1124-5488
Tarcísio FaustoUniversidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas, Departamento de Clínica Médica (Nefrologia), Campinas, SP, Brazil.ORCID http://orcid.org/0000-0002-9699-4710
Sergio Gardano Elias BucharlesUniversidade Federal do Paraná, Departamento de Clínica Médica, Divisão de Nefrologia, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-9051-5045
Melani Ribeiro CustódioUniversidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Laboratório de Fisiopatologia Renal, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-6358-8727
Leandro Lucca JuniorUniversidade de São Paulo, Faculdade de Medicina, Hospital de Clínicas, Ribeirão Preto, SP, Brazil.ORCID http://orcid.org/0000-0001-8236-637X
Fellype de Carvalho BarretoUniversidade Federal do Paraná, Departamento de Clínica Médica, Divisão de Nefrologia, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-6394-9227
Aluízio Barbosa CarvalhoUniversidade Federal de São Paulo, Departamento de Medicina, Divisão de Nefrologia, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-5907-7764
Vanda JorgettiUniversidade Federal do Paraná, Departamento de Clínica Médica, Divisão de Nefrologia, Curitiba, PR, Brazil.ORCID http://orcid.org/0000-0002-4824-8879
José Andrade Moura NetoEscola Bahiana de Medicina e Saúde Pública, Salvador, BA, Brazil.ORCID http://orcid.org/0000-0001-9655-2659
Rodrigo Bueno de OliveiraUniversidade Estadual de Campinas (UNICAMP), Faculdade de Ciências Médicas, Laboratório para o Estudo Mineral e Ósseo em Nefrologia (LEMON), Campinas, SP, Brazil.ORCID http://orcid.org/0000-0002-8273-6200

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic kidney disease (CKD) may lead to secondary hyperparathyroidism (SHP) and its treatment is based on the control of hyperphosphatemia, hypocalcemia, and serum parathormone hormone levels (PTH) levels. Despite the advances in SHP treatment, therapeutic failure is frequent and CKD patients on dialysis require parathyroidectomy (PTx).

aimTo update the 2011 survey, estimate the current prevalence of SHP in Brazilian dialysis centers, verify access to drugs, and identify obstacles to performing PTx.

methodsA questionnaire was sent to active dialysis facilities. The results were compiled and statistically compared (p < 0.05).

resultsA total of 114 facilities successfully responded to the questionnaire, most of them in the Southeast region. Approximately 9% of the individuals (23,535) had serum PTH levels measurements above 1,000 pg/mL (10.7% were reported in the 2011 survey). A considerable number of the reported difficulties indicated limited availability of pivotal medications for SHP management and the associated complications. Of note, only 2.7% of the individuals were submitted to PTx. For those with PTx indication, the waiting time for the procedure was over two years in 28% of the cases. The main barriers to performing PTx were reported to be the long waiting time for PTx, the shortage of head and neck surgeons, and the lack of ward beds for hospital admissions.

conclusionSome aspects have improved since 2011. However, SHP remains highly prevalent in Brazil, and a significant number of individuals do not have access to PTx or experience long waiting times for this surgical procedure while facing substantial difficulties in obtaining clinical treatment.

Indexed as

Health Services AccessibilityHyperparathyroidism, SecondaryParathyroidectomyRenal Insufficiency, ChronicBrazilFemaleHumansPrevalenceRenal Dialysis

Identifiers

PMID39998901
PMCPMC11855617

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.