Evidence map›Paper›PMID 39998764›Full record

ArticleInternational ophthalmology2025

The role of triglyceride-glucose index in central retinal artery occlusion.

Hatice Aslan Sirakaya, Bekir Ayyildiz, Ibrahim Ismet Sert, Bekir Kucuk, Semra Koca, Ender Sirakaya

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Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Hatice Aslan SirakayaDepartment of Internal Medicine, Health Science University, The Kayseri City Hospital, Kayseri, Turkey. hasirakaya@gmail.com.ORCID http://orcid.org/0000-0001-6933-6459
Bekir AyyildizDepartment of Ophthalmology, Health Science University, The Kayseri City Hospital, Kayseri, Turkey.ORCID http://orcid.org/0000-0001-8533-7910
Ibrahim Ismet SertDepartment of Ophthalmology, Health Science University, The Kayseri City Hospital, Kayseri, Turkey.ORCID http://orcid.org/0009-0008-3536-1013
Bekir KucukDepartment of Ophthalmology, Maya Eye Hospital, Kayseri, Turkey.ORCID http://orcid.org/0000-0002-4185-0656
Semra KocaDepartment of Ophthalmology, Health Science University, The Kayseri City Hospital, Kayseri, Turkey.ORCID http://orcid.org/0000-0002-8275-1507
Ender SirakayaDepartment of Ophthalmology, Health Science University, The Kayseri City Hospital, Kayseri, Turkey.ORCID http://orcid.org/0000-0003-2013-6338

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the correlation between the Triglyceride-Glucose (TyG) index and newly diagnosed cases of central retinal artery occlusion (CRAO) in patients.

methodsThe research involved 51 patients diagnosed with central retinal artery occlusion (CRAO) and a control group consisting of 50 healthy volunteers matched for age and sex. Following a thorough ocular examination, various blood biochemistry and hematological parameters were documented. The TyG index was derived from fasting plasma glucose and triglyceride values.

resultsThe average age was 66.1 ± 8.9 years for individuals with CRAO and 64.9 ± 7.6 years for those in the control group. Significant differences in TyG values were observed between the CRAO and control groups, with the CRAO group exhibiting higher values (8.74 ± 0.17 vs. 8.49 ± 0.22, p<0.001). Upon multivariate analysis, the TyG index emerged as an independent predictor of CRAO (Odds Ratio= 1.84, 95% confidence interval = 1.19 - 4.23; p < 0.001). In receiver operating characteristics analysis, the area under the curve for the TyG index was 0.789. A TyG index exceeding 8.58 predicted CRAO with 78% sensitivity and 68% specificity.

conclusionThe current study demonstrated a notable association between increased TyG index and central retinal artery occlusion (CRAO). Thus, the TyG index could serve as a valuable predictive marker for assessing the risk of CRAO.

Indexed as

Blood GlucoseRetinal Artery OcclusionTriglyceridesAgedBiomarkersCase-Control StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesROC CurveBiomarkersBlood GlucoseTriglyceridesCentral retinal artery occlusionCRAOTyG indexVascular disease

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.