Evidence map›Paper›PMID 39998632›Full record

ReviewPediatric nephrology (Berlin, Germany)2025

Kidney involvement during the course of febrile urinary tract infection.

Gaia Pietropaolo, Anna Di Sessa, Paola Tirelli, Emanuele Miraglia Del Giudice, Stefano Guarino, Pierluigi Marzuillo

Abstract readReview
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gaia PietropaoloDepartment of Woman, Child and of General and Specialized Surgery, Università Degli Studi Della Campania "Luigi Vanvitelli", Via Luigi De Crecchio 2, 80138, Naples, Italy.
Anna Di SessaDepartment of Woman, Child and of General and Specialized Surgery, Università Degli Studi Della Campania "Luigi Vanvitelli", Via Luigi De Crecchio 2, 80138, Naples, Italy.
Paola TirelliDepartment of Woman, Child and of General and Specialized Surgery, Università Degli Studi Della Campania "Luigi Vanvitelli", Via Luigi De Crecchio 2, 80138, Naples, Italy.
Emanuele Miraglia Del GiudiceDepartment of Woman, Child and of General and Specialized Surgery, Università Degli Studi Della Campania "Luigi Vanvitelli", Via Luigi De Crecchio 2, 80138, Naples, Italy.
Stefano GuarinoDepartment of Woman, Child and of General and Specialized Surgery, Università Degli Studi Della Campania "Luigi Vanvitelli", Via Luigi De Crecchio 2, 80138, Naples, Italy.
Pierluigi MarzuilloDepartment of Woman, Child and of General and Specialized Surgery, Università Degli Studi Della Campania "Luigi Vanvitelli", Via Luigi De Crecchio 2, 80138, Naples, Italy. pierluigi.marzuillo@unicampania.it.ORCID 0000-0003-4682-0170

Funding

Università degli Studi della Campania Luigi Vanvitelli
6 · The paper itself

Abstract

Febrile urinary tract infections (fUTIs) are among the most common severe infections in the pediatric population, posing a significant risk to kidney health. The pathophysiology of fUTIs involves the direct bacterial invasion of kidney tissue, which triggers an inflammatory response. While this response is effective in eradicating the infection, it can also cause substantial kidney damage at multiple levels. In this review, we explore the various forms of kidney involvement in fUTIs, along with their clinical, radiological, and biochemical presentations. We also discuss the implications of these events for the long-term prognosis of kidney function. Understanding these manifestations can assist clinicians in making prompt diagnoses and initiating appropriate treatment to minimize complications such as sepsis, kidney scarring, and long-term kidney damage.

Indexed as

FeverKidneyKidney DiseasesUrinary Tract InfectionsChildHumansPrognosisAbdominal abscessAcute kidney injuryFeverPseudohypoaldosteronismUrinary tract infection

Identifiers

PMID39998632
PMCPMC12187806

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.