Evidence map›Paper›PMID 39998496›Full record

Trial reportAmerican journal of respiratory and critical care medicine2025

Elastance May Determine the Neuromuscular Blockade Effect on Mortality in Acute Respiratory Distress Syndrome.

Ann A Zalucky, Jose Dianti, Lucile P A Neyton, Pratik Sinha, Kathleen D Liu, Michael A Matthay, B Taylor Thompson, Ewan C Goligher, Carolyn S Calfee

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Reply to SunAmerican journal of respiratory and critical care medicine · 2025
    Article
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  17. Respiratory Mechanics and Mortality during Assisted Ventilation.American journal of respiratory and critical care medicine · 2025
    Article
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  20. American journal of respiratory and critical care medicine · 2025
    Article
4 · The record

Corrections and comments

  • Commented on by
    2025
5 · Who and what money

Authors and funding

9 authors.

Ann A ZaluckyDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine and.ORCID 0000-0002-8247-1361
Jose DiantiInterdepartmental Division of Critical Care Medicine, Department of Medicine, Surgery, Anaesthesia, and Paediatrics, and.ORCID 0000-0003-2016-7003
Lucile P A NeytonDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine and.ORCID 0000-0003-1273-2228
Pratik SinhaDivision of Clinical and Translational Research and Division of Critical Care, Department of Anaesthesiology, Washington University School of Medicine, Saint Louis, Missouri.
Kathleen D LiuDivision of Nephrology, Department of Medicine, and.
Michael A MatthayDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine and.
B Taylor ThompsonDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Massachusetts General Hospital, Harvard School of Medicine, Boston, Massachusetts; and.
Ewan C GoligherInterdepartmental Division of Critical Care Medicine, Department of Medicine, Surgery, Anaesthesia, and Paediatrics, and.ORCID 0000-0002-0990-6701
Carolyn S CalfeeDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine and.

Funding

Precision Medicine in the Acute Respiratory Distress SyndromeR35HL140026 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CALFEE, CAROLYN · 2018 to 2024
$6.8M
Precision Medicine in Sepsis with Critical IllnessR35GM142992 · NIGMS · WASHINGTON UNIVERSITY · PI Pratik Sinha · 2021 to 2026
$2.4M
National Heart, Lung, and Blood Institute PETAL Network R35HL140026NHLBI NIH HHS R35 HL140026NIGMS NIH HHS R35 GM142992
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Neuromuscular BlockadeRespiratory Distress SyndromeAgedBayes TheoremBiomarkersFemaleHumansMaleMiddle AgedNeuromuscular Blocking AgentsBiomarkersNeuromuscular Blocking Agentsbiomarkers of lung injuryheterogeneity of treatment effectmechanical ventilationrespiratory system elastanceventilator-induced lung injury

Identifiers

PMID39998496
PMCPMC12175940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.