Evidence map›Paper›PMID 39998486›Full record

ArticleeLife2025

A VgrG2b fragment cleaved by caspase-11/4 promotes

Yan Qian, Qiannv Liu, Xiangyun Cheng, Chunlei Wang, Chun Kong, Mengqian Li, Chao Ren, Dong Jiang, Shuo Wang, Pengyan Xia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan Qian *Department of Immunology, School of Basic Medical Sciences, Peking University, Beijing, China.ORCID https://orcid.org/0009-0005-7956-8938
Qiannv Liu *Department of Immunology, School of Basic Medical Sciences, Peking University, Beijing, China.
Xiangyun ChengDepartment of Sports Medicine, Peking University Third Hospital, Beijing, China.
Chunlei WangDepartment of Immunology, School of Basic Medical Sciences, Peking University, Beijing, China.
Chun KongDepartment of Immunology, School of Basic Medical Sciences, Peking University, Beijing, China.
Mengqian LiDepartment of Immunology, School of Basic Medical Sciences, Peking University, Beijing, China.
Chao RenDepartment of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Dong JiangDepartment of Sports Medicine, Peking University Third Hospital, Beijing, China.
Shuo WangCAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Pengyan XiaDepartment of Immunology, School of Basic Medical Sciences, Peking University, Beijing, China.ORCID https://orcid.org/0000-0001-7959-5796

Funding

CAS Project for Young Scientists in Basic Research YSBR-010Key Research Program of Frontier Science, Chinese Academy of Sciences ZDBS-LY-SM025National Key Research and Development Program of China 2021YFA1300202National Key Research and Development Program of China 2022YFC2302900National Natural Science Foundation of China 82271790National Natural Science Foundation of China 92169113National Natural Science Foundation of China 92369104Natural Science Foundation of Beijing Municipality 7212067Natural Science Foundation of Beijing Municipality JQ23028Strategic Priority Research Programs of the Chinese Academy of Sciences XDB29020000
6 · The paper itself

Abstract

The T6SS of

Indexed as

Bacterial ProteinsCaspasesCaspases, InitiatorInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinPseudomonas aeruginosaPseudomonas InfectionsAnimalsHumansMacrophagesMiceMice, Inbred C57BLNIMA-Related KinasesBacterial ProteinsCasp4 protein, mouseCaspasesCaspases, InitiatorInflammasomesNek7 protein, mouseNIMA-Related KinasesNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mousecaspase-11/4humanimmunologyinflammationmouseNLRP3non-canonical inflammasomeP. aeruginosaVgrG2b

Identifiers

PMID39998486
PMCPMC11856931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.