Evidence map›Paper›PMID 39998267›Full record

ArticlemBio2025

Quorum sensing employs a dual regulatory mechanism to repress T3SS gene expression.

Payel Paul, Ram Podicheti, Logan J Geyman, Elizabeth N Baker, Kai Papenfort, Douglas B Rusch, Julia C van Kessel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Payel PaulDepartment of Biology, Indiana University Bloomington, Bloomington, Indiana, USA.ORCID 0000-0001-8015-6440
Ram PodichetiCenter for Genomics and Bioinformatics, Indiana University, Bloomington, Indiana, USA.
Logan J GeymanDepartment of Biology, Indiana University Bloomington, Bloomington, Indiana, USA.
Elizabeth N BakerSchool of Medicine, Indiana University, Indianapolis, Indiana, USA.
Kai PapenfortInstitute of Microbiology, Friedrich Schiller University, Jena, Thuringia, Germany.ORCID 0000-0002-5560-9804
Douglas B RuschCenter for Genomics and Bioinformatics, Indiana University, Bloomington, Indiana, USA.ORCID 0000-0002-1066-2687
Julia C van KesselDepartment of Biology, Indiana University Bloomington, Bloomington, Indiana, USA.ORCID 0000-0002-1612-2403

Funding

Quorum sensing regulation of bacterial developmentR35GM124698 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Julia C. van Kessel · 2017 to 2026
$4.1M
Deutsche Forschungsgemeinschaft (DFG) 503931087, 390713860EC | European Research Council (ERC) CoG-101088027HHS | National Institutes of Health (NIH) R35GM124698National Science Foundation (NSF) GRFPNIGMS NIH HHS R35 GM124698
6 · The paper itself

Abstract

The type III secretion system (T3SS) is a needle-like complex used by numerous bacterial pathogens in host infection to inject exotoxins into the host cell cytoplasm. The T3SS is a known virulence factor in the shrimp pathogen IMPORTANCE:

Indexed as

Gene Expression Regulation, BacterialQuorum SensingRepressor ProteinsType III Secretion SystemsVibrioBacterial ProteinsPromoter Regions, GeneticTrans-ActivatorsTranscription FactorsBacterial ProteinsLuxR autoinducer binding proteinsRepressor ProteinsTrans-ActivatorsTranscription FactorsType III Secretion Systemsquorum sensingT3SStype III secretionVibrioVibrio campbellii

Identifiers

PMID39998267
PMCPMC11980564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.