Evidence map›Paper›PMID 39998206›Full record

ArticlemBio2025

Dual function of

Robert Zarnowski, Mark V Horton, Chad J Johnson, Por Choua Vang, Jeremy Uram, Liyanage Devthilini Pasasum Fernando, Jiri Vlach, Christian Heiss, Parastoo Azadi, Jeniel E Nett and 1 more

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Insights on molecular drivers of phenotypic plasticity in Candidozyma auris.World journal of microbiology & biotechnology · 2026
    Review
  2. Microbiology and molecular biology reviews : MMBR · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Robert ZarnowskiDepartment of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-6343-1500
Mark V HortonDepartment of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Chad J JohnsonDepartment of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Por Choua VangDepartment of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Jeremy UramDepartment of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Liyanage Devthilini Pasasum FernandoComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Jiri VlachComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Christian HeissComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Parastoo AzadiComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Jeniel E NettDepartment of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-8587-6244
David R AndesDepartment of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-7927-9950

Funding

Vesicle-mediated drug resistance of Candida albicans biofilmR01AI073289 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI ANDES, DAVID R, MITCHELL, AARON P · 2008 to 2025
$7.9M
National Glycoscience Resource- CCRC Service and Training - NGlycoR@CCRCR24GM137782 · NIGMS · UNIVERSITY OF GEORGIA · PI Parastoo Azadi · 2020 to 2026
$5.2M
Mechanism(s) of pathogenicity for Candida aurisR01AI145939 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI NETT, JENIEL E · 2020 to 2025
$2.7M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01 AI073289-16, R01 AI145939NIAID NIH HHS R01 AI073289NIAID NIH HHS R01 AI145939NIGMS NIH HHS R24 GM137782
6 · The paper itself

Abstract

Screen of mutants from a mannosyltransferase family identified the importance of IMPORTANCE:

Indexed as

Antifungal AgentsBiofilmsCandida aurisFungal ProteinsMannosyltransferasesCell WallChitinDrug Resistance, FungalGlucansHumansImmune EvasionMannansNeutrophilsAntifungal AgentsChitinFungal ProteinsGlucansMannansMannosyltransferasesbiofilmsCandida auriscell walldrug resistance mechanismsextracellular matrixhost response

Identifiers

PMID39998206
PMCPMC11980391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.