Evidence map›Paper›PMID 39998180›Full record

ArticlemBio2025

Nutrition-induced changes in the microbiota can cause dysbiosis and disease development.

Tim Lachnit, Laura Ulrich, Fiete M Willmer, Tim Hasenbein, Leon X Steiner, Maria Wolters, Eva M Herbst, Peter Deines

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. [The Oral Microbiome: Maintenance of Homeostasis, Disease Associations, and Mechanisms of Pathogenesis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Assembly of a functional neuronal circuit in embryos of an ancestral metazoan is influenced by temperature and the microbiome.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tim LachnitZoological Institute, Christian-Albrechts-University Kiel, Kiel, Germany.ORCID 0000-0002-2880-5930
Laura UlrichInstitute of Human Genetics, University Hospital Schleswig-Holstein, Kiel, Germany.
Fiete M WillmerZoological Institute, Christian-Albrechts-University Kiel, Kiel, Germany.
Tim HasenbeinInstitute of Pharmacology and Toxicology, Technical University of Munich, München, Germany.
Leon X SteinerRU Marine Symbioses, RD3 Marine Ecology, GEOMAR Helmholtz Centre for Ocean Research, Kiel, Germany.
Maria WoltersFakultät Nachhaltigkeit, Leuphana Universität Lüneburg, Lüneburg, Germany.
Eva M HerbstExperimental Orthopedics and Trauma Surgery, University Hospital Schleswig-Holstein, Kiel, Germany.
Peter DeinesZoological Institute, Christian-Albrechts-University Kiel, Kiel, Germany.ORCID 0000-0003-0926-489X

Funding

Deutsche Forschungsgemeinschaft (DFG) Project-ID 261376515 - SFB 1182
6 · The paper itself

Abstract

Eukaryotic organisms are associated with complex microbial communities. Changes within these communities have been implicated in disease development. Nonetheless, it remains unclear whether these changes are a cause or a consequence of disease. Here, we report a causal link between environment-induced shifts in the microbiota and disease development. Using the model organism

Indexed as

DysbiosisHydraMicrobiotaAnimalsArginineHost Microbial InteractionsLakesPseudomonasSymbiosisArgininediseasedysbiosisenvironmenthost-microbe interactioninflammationmicrobiomemicrobiotanutritionpathogens

Identifiers

PMID39998180
PMCPMC11980362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.