Evidence map›Paper›PMID 39998099›Full record

ArticleToxins2025

Innovative Mycotoxin Detoxifying Agents Decrease the Absorption Rate of Aflatoxin B1 and Counteract the Oxidative Stress in Broiler Chickens Exposed to Low Dietary Levels of the Mycotoxin.

Matteo Cuccato, Neenu Amminikutty, Veronica Spalenza, Vanessa Conte, Stefano Bagatella, Donato Greco, Vito D'Ascanio, Francesco Gai, Achille Schiavone, Giuseppina Avantaggiato and 2 more

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Efficacy of Toxfin in Mitigating Mycotoxin Effects in Laying Hens.Animals : an open access journal from MDPI · 2026
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Matteo CuccatoDepartment of Veterinary Sciences, University of Torino, 10095 Grugliasco, Italy.ORCID 0000-0001-8431-0695
Neenu AmminikuttyDepartment of Veterinary Sciences, University of Torino, 10095 Grugliasco, Italy.ORCID 0009-0003-4353-2963
Veronica SpalenzaDepartment of Veterinary Sciences, University of Torino, 10095 Grugliasco, Italy.
Vanessa ConteDepartment of Veterinary Sciences, University of Torino, 10095 Grugliasco, Italy.
Stefano BagatellaDepartment of Veterinary Sciences, University of Torino, 10095 Grugliasco, Italy.
Donato GrecoInstitute of Sciences of Food Production, Italian National Research Council, 70126 Bari, Italy.ORCID 0000-0002-8681-1263
Vito D'AscanioInstitute of Sciences of Food Production, Italian National Research Council, 70126 Bari, Italy.ORCID 0000-0001-7344-9712
Francesco GaiInstitute of Sciences of Food Production, National Research Council, 10095 Grugliasco, Italy.ORCID 0000-0003-1037-9483
Achille SchiavoneDepartment of Veterinary Sciences, University of Torino, 10095 Grugliasco, Italy.ORCID 0000-0002-8011-6999
Giuseppina AvantaggiatoInstitute of Sciences of Food Production, Italian National Research Council, 70126 Bari, Italy.ORCID 0000-0003-0756-7272
Carlo NebbiaDepartment of Veterinary Sciences, University of Torino, 10095 Grugliasco, Italy.ORCID 0000-0003-0624-7787
Flavia GirolamiDepartment of Veterinary Sciences, University of Torino, 10095 Grugliasco, Italy.ORCID 0000-0001-9005-5301

Funding

European Commission H2020-EU.3.2
6 · The paper itself

Abstract

Aflatoxin B1 (AFB1) can impair the growth of chickens and reduce the quality of eggs and meat, resulting in significant economic losses. The inclusion of mycotoxin detoxifying agents (MyDA) with binding properties in the diet is an efficient tool to reduce their absorption rate in the gastrointestinal tract. Our aim was to investigate the ability of two innovative MyDA (SeOX, a feed additive featuring a tri-octahedral smectite mixed with lignocellulose, and CHS, a di-octahedral smectite functionalized with an organic non-toxic modifier) in both reducing the bio-accessibility and mitigating the adverse effects of AFB1 in broilers exposed for 10 days to concentrations approaching the European Union maximum limits in feed (0.02 mg/kg). The amount of AFB1 in the excreta of birds, collected over four consecutive days (starting on day 7), was significantly lower (

Indexed as

Aflatoxin B1Oxidative StressAnimal FeedAnimalsChickensFood ContaminationMaleAflatoxin B1aflatoxin B1chickendrug-metabolizing enzymeslivermycotoxin detoxifying agentsoxidative stress

Identifiers

PMID39998099
PMCPMC11861810

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.