Evidence map›Paper›PMID 39998092›Full record

ArticleToxins2025

Metabolomic Profiling of Human Urine Related to Mycotoxin Exposure.

Nuria Dasí-Navarro, Sonia Lombardi, Pilar Vila-Donat, Sabrina Llop, Jesus Vioque, Raquel Soler-Blasco, Ana Esplugues, Lara Manyes, Manuel Lozano

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nuria Dasí-NavarroBiotech Agrifood, Faculty of Pharmacy and Food Sciences, University of Valencia, 46100 Burjassot, Spain.ORCID 0000-0002-3313-1803
Sonia LombardiDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-4447-0798
Pilar Vila-DonatBiotech Agrifood, Faculty of Pharmacy and Food Sciences, University of Valencia, 46100 Burjassot, Spain.ORCID 0000-0002-1496-3508
Sabrina LlopEpidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, 46020 València, Spain.
Jesus VioqueSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0002-2284-148X
Raquel Soler-BlascoEpidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, 46020 València, Spain.
Ana EspluguesEpidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, 46020 València, Spain.
Lara ManyesBiotech Agrifood, Faculty of Pharmacy and Food Sciences, University of Valencia, 46100 Burjassot, Spain.ORCID 0000-0001-5777-6107
Manuel LozanoBiotech Agrifood, Faculty of Pharmacy and Food Sciences, University of Valencia, 46100 Burjassot, Spain.ORCID 0000-0003-2046-5959

Funding

Generalitat Valenciana GV/2021/111, CIACO 2021/132 and EDGJID/2021/112Instituto de Salud Carlos III FIS-FEDER: 13/1944, 16/1288, 17/00663, 19/1338 and 23/1578; FIS-FSE: 17/00260; Miguel Servet-FSE: MSII20/0006Ministry of Universities CAS21/00008
6 · The paper itself

Abstract

Human exposure to mycotoxins is a global concern since several mycotoxins, such as enniatins and aflatoxins, have shown carcinogenic and neurotoxic effects, and the toxicologic mechanisms of most of them still need to be clarified. This study aims to investigate the metabolic pathways affected by mycotoxin exposure by evaluating metabolite alterations in urine. The participants were 540 women from the Spanish Childhood and Environment Project (INMA). For metabolite identification, a dilute and shoot extraction, followed by HPLC-Q-TOF-MS identification analysis, was performed. Data were processed using Agilent Mass Hunter Workstation with the METLIN database, Agilent Mass Profiler Professional 10.0, and Metaboanalyst 6.0. Over 2000 metabolites were obtained in each sample after feature extraction, and the most significant metabolites (

Indexed as

Environmental ExposureMetabolomeMycotoxinsAdultFemaleHumansMetabolomicsMiddle AgedYoung AdultMycotoxinsbiomonitoringHPLC-Q-TOF-MSmetabolomicsmycotoxinsurine

Identifiers

PMID39998092
PMCPMC11860571

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.