Evidence map›Paper›PMID 39997954›Full record

ArticleToxics2025

Ambient Air Pollution and Parkinson's Disease and Alzheimer's Disease: An Updated Meta-Analysis.

Cuiyao Xie, Xi Xia, Kai Wang, Jie Yan, Lijun Bai, Liqiong Guo, Xiaoxue Li, Shaowei Wu

Abstract read
In one paragraph

Article in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cuiyao XieDepartment of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Xi XiaDepartment of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Kai WangDepartment of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Jie YanDepartment of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Lijun BaiDepartment of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Liqiong GuoSchool of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China.ORCID 0000-0002-1141-9646
Xiaoxue LiDisaster Medicine Research Center, Medical Innovation Research Division of the Chinese PLA General Hospital, Beijing 100853, China.
Shaowei WuDepartment of Occupational and Environmental Health, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.ORCID 0000-0003-2680-6064

Funding

the National Key Research & Development Programs of China 2023YFC3604701/2023YFC3604700, 2023YFE0117400the National Natural Science of China 82273587, 81971416the Youth Top Talent Program of Xi'an Jiaotong University 202010
6 · The paper itself

Abstract

backgroundPrevious epidemiological evidence regarding the associations between ambient air pollution and two major neurodegenerative diseases, Alzheimer's disease (AD) and Parkinson's disease (PD), remains inconclusive.

objectiveThis study aimed to evaluate the associations between long-term and short-term exposure to PM

methodsA random-effects model was used to summarize individual effect estimates in the meta-analysis. A subgroup meta-analysis was further conducted to explore the potential sources of heterogeneity.

resultsIn total, 42 eligible studies were included. For each 5 μg/m

conclusionAmbient air pollution, particularly PM

Indexed as

Alzheimer’s diseaseambient air pollutionmeta-analysisParkinson’s diseaseparticulate matter

Identifiers

PMID39997954
PMCPMC11861764

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.