Evidence map›Paper›PMID 39997949›Full record

ReviewToxics2025

Non-Invasive Matrices for the Human Biomonitoring of PFAS: An Updated Review of the Scientific Literature.

Martí Nadal, José L Domingo

Abstract readReview
In one paragraph

Review in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Martí NadalLaboratory of Toxicology and Environmental Health, School of Medicine, TecnATox, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Catalonia, Spain.ORCID 0000-0002-0217-4827
José L DomingoLaboratory of Toxicology and Environmental Health, School of Medicine, TecnATox, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Catalonia, Spain.ORCID 0000-0001-6647-9470

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals widely used in consumer and industrial products due to their unique physicochemical properties. However, their persistence and bioaccumulative potential pose significant environmental and human health risks. This review focuses on the use of non-invasive matrices-urine, hair, and nails-for the human biomonitoring of PFAS, highlighting key findings from scientific studies. While urine offers a non-invasive and practical option, its limited sensitivity for long-chain PFAS requires further analytical advances. Hair and nails have demonstrated potential for use in biomonitoring, with higher detection frequencies and concentrations for certain PFAS compared to urine. The variability in PFAS levels across studies reflects differences in population characteristics, exposure sources, and geographic regions. This review emphasizes the need for standardized analytical methods, expanded population studies, and the use of complementary matrices to enhance the accuracy and reliability of PFAS exposure assessment.

Indexed as

environmental exposurehairhuman biomonitoringnailsper- and polyfluoroalkyl substances (PFAS)urine

Identifiers

PMID39997949
PMCPMC11860639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.