Evidence map›Paper›PMID 39997745›Full record

ArticleMetabolites2025

Multi-Omics Approach to Evaluate Effects of Dietary Sodium Butyrate on Antioxidant Capacity, Immune Function and Intestinal Microbiota Composition in Adult Ragdoll Cats.

Anxuan Zhang, Deping Li, Tong Yu, Mingrui Zhang, Yingyue Cui, Haotian Wang, Tianyu Dong, Yi Wu

Abstract read
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anxuan ZhangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Deping LiHangzhou Netease Yanxuan Trading Co., Ltd., Hangzhou 310051, China.
Tong YuState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Mingrui ZhangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.ORCID 0000-0003-2525-6590
Yingyue CuiState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Haotian WangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Tianyu DongState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Yi WuState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-2105-8629

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSodium butyrate (SB) is a typical postbiotic known to positively affect economic animals in recent years, but research on SB in pet cats is scarce. Consequently, this study sought to explore the influence of SB on anti-inflammatory and antioxidant capacity, immune function, and gut microbiota of adult cats through the assessment of biochemical parameters and comprehensive integrative omics analysis.

methodsA total of 30 adult cats were divided into three groups: a basal diet (NC), basal diet with 0.05% SB (SB5), and basal diet with 0.1% SB (SB10). The experiment lasted for 6 weeks.

resultsThe results indicated that the fecal level of calprotectin was lower in the SB10 group than in the SB5 and NC groups. The SB10 group reduced the serum levels of TNF-α, IL-1β and DAO compared with the NC group (

conclusionsDietary SB could enhance the antioxidant and anti-inflammatory capacity, improve immune function, and positively regulate the gut microbiota composition in adult cats.

Indexed as

adult catantioxidant capacitygut microbiotaimmune functionsodium butyrate

Identifiers

PMID39997745
PMCPMC11857798

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.