Evidence map›Paper›PMID 39997701›Full record

ArticleMetabolites2025

Hypoxia Dependent Inhibition of Glioblastoma Cell Proliferation, Invasion, and Metabolism by the Choline-Kinase Inhibitor JAS239.

Claire Louise Kelly, Martyna Wydrzynska, Marie M Phelan, Sofya Osharovich, Edward J Delikatny, Violaine Sée, Harish Poptani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Claire Louise KellyCentre for Preclinical Imaging, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool L69 3BX, UK.
Martyna WydrzynskaCentre for Cell Imaging, Department of Biochemistry & Systems Biology, University of Liverpool, Liverpool L69 7BE, UK.
Marie M PhelanHigh Field NMR Facility, Department of Biochemistry & Systems Biology, University of Liverpool, Liverpool L69 7ZX, UK.ORCID 0000-0002-0708-2964
Sofya OsharovichDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Edward J DelikatnyDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Violaine SéeCentre for Cell Imaging, Department of Biochemistry & Systems Biology, University of Liverpool, Liverpool L69 7BE, UK.ORCID 0000-0001-6384-8381
Harish PoptaniCentre for Preclinical Imaging, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool L69 3BX, UK.ORCID 0000-0002-0593-3235

Funding

Near-infrared Choline Kinase Sensors for Intraoperative Identification of Lung Tumor MarginsR01CA226412 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DELIKATNY, EDWARD J, SINGHAL, SUNIL · 2018 to 2022
$1.8M
NCI NIH HHS R01 CA226412North West Cancer Research PhD Studentship
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

3D spheroidscell cyclecell invasioncell trackingcholine kinase inhibitorglioblastomahypoxiametabolismmetabolomics

Identifiers

PMID39997701
PMCPMC11857610

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.