Assessment of Endocyn on Dental Pulp Stem Cells (DPSCs): A Pilot Study of Endodontic Irrigant Effects.

Brennan Truman, Linda Ma, Samuel Stewart, Karl Kingsley, Victoria Sullivan

Abstract read

In one paragraph

Article in Methods and protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brennan TrumanDepartment of Advanced Education in Pediatric Dentistry, School of Dental Medicine, University of Nevada, 1700 West Charleston Blvd, Las Vegas, NV 89106, USA.

Linda MaDepartment of Clinical Sciences, School of Dental Medicine, University of Nevada, 1700 West Charleston Blvd, Las Vegas, NV 89106, USA.

Samuel StewartDepartment of Clinical Sciences, School of Dental Medicine, University of Nevada, 1700 West Charleston Blvd, Las Vegas, NV 89106, USA.

Karl KingsleyDepartment of Biomedical Sciences, School of Dental Medicine, University of Nevada, 1001 Shadow Lane, Las Vegas, NV 89106, USA.ORCID 0000-0002-1036-7522

Victoria SullivanDepartment of Advanced Education in Pediatric Dentistry, School of Dental Medicine, University of Nevada, 1700 West Charleston Blvd, Las Vegas, NV 89106, USA.ORCID 0000-0003-3094-5665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many endodontic procedures within the pediatric population are performed with patients aged 12 years and older, using intracanal irrigants to complement mechanical debridement for the removal of debris and to disinfect the root canal system. The use of antimicrobial irrigants that limit damage to the dental pulp are the goals of endodontic biomaterials research. Using an existing biorepository of dental pulp stem cells (DPSCs), Endocyn was evaluated in varying concentrations in proliferation and viability assays, and compared with positive (sodium hypochlorite or bleach) and negative (phosphate-buffered saline) controls. The DPSC viability was reduced in the range of -8.3% to -15.8%,

Indexed as

dental pulp stem cellsdisinfection methodEndocynendodontic irrigant

Identifiers

PMID39997642

DOI10.3390/mps8010018

PMCPMC11858511

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.