Evidence map›Paper›PMID 39997636›Full record

ArticleMethods and protocols2025

Procurement, Processing, and Storage of Human Amniotic Membranes for Implantation Purposes in Non-Healing Pressure Ulcers.

Lina A Gómez, Carlos Domínguez-Paz, Juan F Ospina, Elga J Vargas

Abstract read
In one paragraph

Article in Methods and protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lina A GómezBiomedical Research Center (CIBUS), Faculty of Medicine, Universidad de La Sabana, Chía 53753, Colombia.
Carlos Domínguez-PazDepartment of Prototypes and Manufacturing, Grupo de Energia, Materiales y Ambiente (GEMA), Universidad de La Sabana, Chía 140013, Colombia.ORCID 0000-0002-2068-8530
Juan F OspinaHospital Universitario La Samaritana, Ginecohus Research Group, Bogotá 111321, Colombia.
Elga J VargasPathology Laboratory, Department of Pathology, Faculty of Medicine, Universidad de La Sabana, Chía 140013, Colombia.ORCID 0000-0001-5254-2256

Funding

Universidad de La Sabana Universidad de La Sabana
6 · The paper itself

Abstract

The human amniotic membrane (hAM) has been used as an implant to enhance the regenerative process and control inflammation in different diseases, given their structure, biocompatibility, presence of stem cells and multiple growth factors. The objective of this study was to generate a standardized protocol for obtaining, processing, and storing hAMs that guarantee the conservation of their structural and cellular characteristics as well as their mechanical properties, ensuring their ease of handling, sterility, and quality that allows their implementation for therapeutic purposes in the field of regenerative medicine. The hAMs were obtained from mothers with healthy, full-term, controlled pregnancies and by cesarean section. The hAMs were processed under sterile conditions, manually separated from the placenta and, subsequently, they were frozen in a solution of culture medium plus 50%

Indexed as

amniotic membranepreparationprocurementpropertiesregenerative medicinetissue engineeringwoundwound carewound healing

Identifiers

PMID39997636
PMCPMC11858804

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.