Evidence map›Paper›PMID 39997592›Full record

ArticleJournal of functional biomaterials2025

Enhancing Bone Repair: Impact of Raloxifene-Functionalized Cerabone

Laura Gabriela Macedo, Gabriel Mulinari-Santos, Natália Barbosa de Siqueira, Letícia Pitol-Palin, Ana Cláudia Ervolino da Silva, Paula Buzo Frigério, Paulo Roberto Botacin, Paulo Noronha Lisboa-Filho, Roberta Okamoto

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura Gabriela MacedoDepartment of Basic Sciences, Araçatuba School of Dentistry, São Paulo State University "Júlio de Mesquita Filho", Araçatuba 16018-805, SP, Brazil.
Gabriel Mulinari-SantosDepartment of Basic Sciences, Araçatuba School of Dentistry, São Paulo State University "Júlio de Mesquita Filho", Araçatuba 16018-805, SP, Brazil.ORCID 0000-0003-4489-6868
Natália Barbosa de SiqueiraDepartment of Diagnosis and Surgery, Araçatuba School of Dentistry, São Paulo State University "Júlio de Mesquita Filho", Araçatuba 16015-050, SP, Brazil.
Letícia Pitol-PalinDepartment of Diagnosis and Surgery, Araçatuba School of Dentistry, São Paulo State University "Júlio de Mesquita Filho", Araçatuba 16015-050, SP, Brazil.ORCID 0000-0003-4765-3765
Ana Cláudia Ervolino da SilvaDepartment of Diagnosis and Surgery, Araçatuba School of Dentistry, São Paulo State University "Júlio de Mesquita Filho", Araçatuba 16015-050, SP, Brazil.
Paula Buzo FrigérioDepartment of Diagnosis and Surgery, Araçatuba School of Dentistry, São Paulo State University "Júlio de Mesquita Filho", Araçatuba 16015-050, SP, Brazil.ORCID 0000-0002-5012-5093
Paulo Roberto BotacinDepartment of Basic Sciences, Araçatuba School of Dentistry, São Paulo State University "Júlio de Mesquita Filho", Araçatuba 16018-805, SP, Brazil.
Paulo Noronha Lisboa-FilhoDepartment of Physics, Bauru School of Sciences, São Paulo State University "Júlio de Mesquita Filho", Bauru 17033-360, SP, Brazil.ORCID 0000-0002-7734-4069
Roberta OkamotoDepartment of Basic Sciences, Araçatuba School of Dentistry, São Paulo State University "Júlio de Mesquita Filho", Araçatuba 16018-805, SP, Brazil.ORCID 0000-0002-6773-6966

Funding

"National Council for Scientific and Technological Development - CNPq" - fellowship Roberta Okamoto 308408/2023-3São Paulo Research Foundation - FAPESP 2021/12852-8
6 · The paper itself

Abstract

Bone substitutes are commonly used in bone regeneration, and their functionalization with bioactive molecules can significantly enhance bone regeneration by directly influencing bone cells. This study aimed to evaluate the potential of raloxifene-functionalized Cerabone

Indexed as

bonebone substitutesraloxifenewound healing

Identifiers

PMID39997592
PMCPMC11856733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.