ArticleJournal of imaging2025
Differentiation of Atypical Lipomatous Tumors from Lipomas: Our Experience with Visual Analysis of Conventional Magnetic Resonance Imaging.
Article in Journal of imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Evaluation of Magnetic Resonance Imaging Features to Distinguish Lipomas from Atypical Lipomatous Tumours in the Extremities and Back.Diagnostics (Basel, Switzerland) · 2026Article
- Fat-containing soft-tissue tumors: Imaging findings and pathologic correlation.Skeletal radiology · 2026Review
- Article
- Intratendinous Lipoma of Biceps Long Head: A Case Report and Current Concepts Review of Musculoskeletal Lipomas.Journal of orthopaedic case reports · 2026Article
- Madelung's disease involving the scrotum: a case report and diagnostic pitfalls with liposarcoma.Frontiers in oncology · 2026Article
- Soft Tissue Masses of the Hand.Seminars in musculoskeletal radiology · 2025Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Differentiating atypical lipomatous tumors (ALTs) from lipomas using imaging techniques is a challenge, and the biopsy with immunohistochemical determination of murine double minute 2 (MDM2) oncogene is the gold standard. We are looking for a management algorithm with the visual analysis of magnetic resonance images in these two fatty soft tissue tumors that allow us to avoid some biopsies. Two radiologists, blinded to the final diagnosis, independently assessed various features on conventional magnetic resonance imaging (MRI), in 79 patients with pathologically confirmed fatty tumors as either lipoma (MDM2 negative) or ALT (MDM2 positive). Results: The interobserver agreement for the most MRI features was moderate and the musculoskeletal radiologist accuracy for final diagnosis was 90% sensitivity and 66% specificity. Tumors with homogeneous fat signals and a maximum size < 8 cm were always lipomas (
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