Evidence map›Paper›PMID 39997474›Full record

ArticleJournal of cardiovascular development and disease2025

Expiration-Triggered Sinus Arrhythmia Predicts Mortality Risk in the General Elderly Population.

Ralf Josef Dirschinger, Alexander Müller, Alexander Steger, Karl-Ludwig Laugwitz, Petra Barthel, Georg Schmidt, Daniel Sinnecker

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ralf Josef DirschingerDepartment of Internal Medicine I, University Hospital rechts der Isar, TUM School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0003-1175-3887
Alexander MüllerDepartment of Internal Medicine I, University Hospital rechts der Isar, TUM School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0001-9090-3374
Alexander StegerDepartment of Internal Medicine I, University Hospital rechts der Isar, TUM School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.
Karl-Ludwig LaugwitzDepartment of Internal Medicine I, University Hospital rechts der Isar, TUM School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.
Petra BarthelDepartment of Internal Medicine I, University Hospital rechts der Isar, TUM School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.
Georg SchmidtDepartment of Internal Medicine I, University Hospital rechts der Isar, TUM School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0003-3692-5243
Daniel SinneckerDepartment Clinical Medicine, TUM School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0002-8116-9750

Funding

Deutsche Forschungsgemeinschaft SFB 386Federal Ministry of Education and Research 13N/7073/7German Heart Research Foundation F/19/16
6 · The paper itself

Abstract

Reduced respiratory sinus arrhythmia, quantified as expiration-triggered sinus arrhythmia (ETA) from simultaneous electrocardiogram and respiration recordings, is a strong long-term mortality predictor in myocardial infarction survivors. Here, we investigated whether ETA also predicts mortality risk in the general elderly population. ETA was quantified from 30-min electrocardiogram and respiration recordings in 1788 general population subjects aged ≥60 years, who were then followed for a median of 4.0 years (median age 72 years, 58% female). Four-year all-cause mortality was 4.6%. Abnormal ETA using a predefined cutoff (≤0.19 ms) was associated with a 4-year mortality of 6.9%, compared to 3.7% in the remaining participants (

Indexed as

cardiac autonomic functionheart rate variabilityphase-rectified signal averagingrespiratory sinus arrhythmiarisk stratification

Identifiers

PMID39997474
PMCPMC11856101

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.