Evidence map›Paper›PMID 39997471›Full record

ArticleJournal of cardiovascular development and disease2025

High-Risk Plaque Characteristics in Patients with Suspected Stable Coronary Artery Disease and Impaired Glucose Tolerance: A Coronary Computed Tomography Angiography Study.

Thomas Rueskov Andersen, Katrine Schultz Overgaard, Laurits Juhl Heinsen, Roda Abdulkadir Mohamed, Freja Sønder Madsen, Helle Precht, Jess Lambrechtsen, Søren Auscher, Kenneth Egstrup

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thomas Rueskov AndersenCardiovascular Research Unit, Odense University Hospital Svendborg, 5700 Svendborg, Denmark.
Katrine Schultz OvergaardCardiovascular Research Unit, Odense University Hospital Svendborg, 5700 Svendborg, Denmark.ORCID 0000-0003-4445-8235
Laurits Juhl HeinsenCardiovascular Research Unit, Odense University Hospital Svendborg, 5700 Svendborg, Denmark.
Roda Abdulkadir MohamedCardiovascular Research Unit, Odense University Hospital Svendborg, 5700 Svendborg, Denmark.ORCID 0000-0003-0003-4801
Freja Sønder MadsenCardiovascular Research Unit, Odense University Hospital Svendborg, 5700 Svendborg, Denmark.ORCID 0009-0003-7705-9035
Helle PrechtCardiovascular Research Unit, Odense University Hospital Svendborg, 5700 Svendborg, Denmark.ORCID 0000-0003-1525-5316
Jess LambrechtsenCardiovascular Research Unit, Odense University Hospital Svendborg, 5700 Svendborg, Denmark.ORCID 0000-0002-9976-9981
Søren AuscherCardiovascular Research Unit, Odense University Hospital Svendborg, 5700 Svendborg, Denmark.ORCID 0000-0003-0399-2503
Kenneth EgstrupCardiovascular Research Unit, Odense University Hospital Svendborg, 5700 Svendborg, Denmark.

Funding

Region of Southern Denmark 697
6 · The paper itself

Abstract

Impaired glucose tolerance (IGT), a prediabetic state, is a known risk factor for coronary artery disease (CAD). Low-attenuation plaque (LAP) lesions are associated with a high risk of coronary events. We aimed to evaluate high-risk plaque characteristics in LAP lesions between patients with IGT and normal glucose tolerance (NGT) in patients suspected for stable CAD. Coronary computed tomography angiography (CCTA) identified LAP lesions and assessed plaque volumes, burdens, and high-risk plaque features. Glycemic tolerance was stratified using oral glucose tolerance tests. Among 148 patients, 202 LAP lesions were identified, with 93 patients classified as NGT and 55 as IGT. Patients with IGT had a significantly higher prevalence of LAP lesions compared with NGT (

Indexed as

coronary artery diseasecoronary CT angiographyhigh-risk plaque featureimpaired glucose tolerancelow-attenuation plaqueprediabetes

Identifiers

PMID39997471
PMCPMC11856177

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.