ArticleJournal of xenobiotics2025
Residential Proximity Land Use Characteristics and Exhaled Volatile Organic Compounds' Impact on Pulmonary Function in Asthmatic Children.
Article in Journal of xenobiotics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundUrban air pollution adversely affects children's respiratory systems, but the impact of volatile organic compounds (VOCs) on children's pulmonary function remains unclear. This study aims to identify exhaled VOCs linked to land use characteristics and reduced pulmonary function in asthmatic children, as well as to explore environmental thresholds influencing VOC exposure levels.
methodsWe enrolled 97 asthmatic children, aged 7 to 20, from Changhua County, Taiwan, and collected personal and residential data, collected exhaled VOC samples, and conducted pulmonary function tests. Land use characteristics were derived from the children's residential addresses. This study used two models to explore the relationships between land use, VOC levels, and pulmonary function.
resultsOur results show that m/p-xylene, 1,3,5-trimethylbenzene, and 1,2,4-trimethylbenzene were key contributors to FEV
conclusionsThis study fills a research gap on low-level outdoor VOC exposure and pediatric respiratory health, examining 1,3,5-trimethylbenzene, 1,2,4-trimethylbenzene, and m/p-xylene as potential biomarkers for impaired pulmonary function in children.
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