Evidence map›Paper›PMID 39997353›Full record

ArticleHematology reports2025

The Role of Ferritin and Folate in Determining Stem Cell Collection for Autologous Stem Cell Transplant in Multiple Myeloma.

Charles J Weeks, Mohammad Mian, Michael Stokes, Matthew Gold, Anvay Shah, Rohan Vuppala, Katherine J Kim, Abigayle B Simon, Jorge Cortes, Anand Jillela and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hematology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Charles J WeeksMedical College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0009-0007-8082-3320
Mohammad MianGeorgia Cancer Center, Augusta University, Augusta, GA 30912, USA.
Michael StokesMedical College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0009-0005-3401-6283
Matthew GoldMedical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Anvay ShahMedical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Rohan VuppalaMedical College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0009-0002-3320-7684
Katherine J KimMedical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Abigayle B SimonMedical College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-7394-2088
Jorge CortesGeorgia Cancer Center, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-8636-1071
Anand JillelaGeorgia Cancer Center, Augusta University, Augusta, GA 30912, USA.
Vamsi KotaGeorgia Cancer Center, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-5290-9289

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn autologous stem cell transplant (ASCT) is the standard of care for eligible patients with multiple myeloma (MM). However, the success of ASCT largely hinges on efficient mobilization; thus, a thorough analysis of factors that may affect mobilization is essential.

methodsThe study consists of a single-center, retrospective chart review of 292 adult patients undergoing their first or second autologous transplantation for MM from 2016 to 2023. Patient demographics, serum lab values at the pre-collection evaluation visit, total stem cell capture (TC) in CD34/kg × 10

resultsIndividuals with high folate levels experienced less DOA (1.43 ± 0.61) compared to those with normal folate levels (1.68 ± 0.82,

conclusionsThe findings reveal that folate, ferritin, and Hgb levels are significantly associated with apheresis outcomes, offering guidance for optimizing stem cell mobilization in patients with MM.

Indexed as

autologous transplantationferritinfolic acidhematopoietic stem cell mobilizationhemoglobinmultiple myeloma

Identifiers

PMID39997353
PMCPMC11855912

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.