Evidence map›Paper›PMID 39997314›Full record

ReviewHealthcare (Basel, Switzerland)2025

Effects of Physical Exercise on Cardiometabolic Health in Individuals with Autism Spectrum Disorder: A Systematic Review.

Léa Charlier, Léa Cordeiro, Jorge Lopes Cavalcante Neto, Étore De Favari Signini, Jordana Barbosa-Silva, Camilo Corbellini, Antoine Lipka, Raphael Martins de Abreu

Abstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Léa CharlierDepartment of Health, LUNEX University of Applied Sciences, 4671 Differdange, Luxembourg.
Léa CordeiroDepartment of Health, LUNEX University of Applied Sciences, 4671 Differdange, Luxembourg.
Jorge Lopes Cavalcante NetoDepartment of Humanities Sciences, University of Bahia State, Jacobina 40411120, Brazil.ORCID 0000-0002-8396-2410
Étore De Favari SigniniDepartment of Physiotherapy, Federal University of São Carlos, São Carlos 13565905, Brazil.ORCID 0000-0002-5355-3309
Jordana Barbosa-SilvaFaculty of Business Management and Social Sciences, University of Applied Sciences-Hochschule Osnabrück, 49076 Osnabrück, Germany.
Camilo CorbelliniDepartment of Health, LUNEX University of Applied Sciences, 4671 Differdange, Luxembourg.ORCID 0000-0002-7476-9301
Antoine LipkaDepartment of Health, LUNEX University of Applied Sciences, 4671 Differdange, Luxembourg.ORCID 0009-0007-9363-3235
Raphael Martins de AbreuDepartment of Health, LUNEX University of Applied Sciences, 4671 Differdange, Luxembourg.ORCID 0000-0003-3130-101X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesIndividuals with autism spectrum disorder (ASD) are at increased risk of developing cardiometabolic diseases. Although physical exercise (PE) has emerged in the literature as an important modulator for reducing such risk, evidence remains unclear. This systematic review aimed to investigate the effects of PE on cardiometabolic health in individuals with ASD.

methodsA systematic review was carried out according to the PRISMA guidelines, from their inception until 18 July 2023, in the following electronic databases: Scopus, Medline, and Web of Science. Studies were included if they focused on ASD patients undergoing physical exercise, assessing cardiometabolic risk, exercise tolerance, and QoL. The following were excluded: non-exercise interventions, additional therapies, non-English studies, and reviews. The methodological quality of the included studies was assessed through the Downs and Black scale.

resultsA total of four studies (149 participants) were included in this review, with the average methodological quality being rated as "fair". Interventions had mixed effects on cardiometabolic health. The BMI (↓2.8 kg/m

conclusionsThis review indicates that aerobic and functional training improves cardiometabolic health, autistic traits, and QoL in individuals with ASD, particularly in mild cases. Further research is needed to explore the impact of ASD severity on these outcomes.

Indexed as

autism spectrum disordercardiorespiratory fitnesscardiovascular healthexercise

Identifiers

PMID39997314
PMCPMC11855590

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.