Evidence map›Paper›PMID 39997294›Full record

ArticleHealthcare (Basel, Switzerland)2025

Clinical Evidence of the Use of Mepolizumab in the Treatment of Chronic Rhinosinusitis with Nasal Polyps: A Prospective Observational Study.

Antonio Moffa, Francesco Iafrati, Lucrezia Giorgi, Domiziana Nardelli, Luca Carnuccio, Peter Baptista, Ewa Olszewska, Manuele Casale

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Efficacy and safety of mepolizumab in the treatment of CRSwNP in the real-life setting: a review of the literature.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  3. Article
  4. Article
  5. Allergen Immunotherapy: Pitfalls, Perks and Unexpected Allies.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antonio MoffaSchool of Medicine, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.
Francesco IafratiSchool of Medicine, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.ORCID 0000-0001-7944-6707
Lucrezia GiorgiIntegrated Therapies in Otolaryngology, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.
Domiziana NardelliSchool of Medicine, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.
Luca CarnuccioSchool of Medicine, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.
Peter BaptistaENT Department, Al Zahra Private Hospital Dubai, Dubai 23614, United Arab Emirates.ORCID 0000-0002-6601-5331
Ewa OlszewskaDepartment of Otolaryngology, Sleep Apnea Surgery Center, Medical University of Bialystok, 15-276 Bialystok, Poland.ORCID 0000-0002-9993-9266
Manuele CasaleSchool of Medicine, Università Campus Bio-Medico di Roma, 00128 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chronic rhinosinusitisMFepolizumabnasal polyps

Identifiers

PMID39997294
PMCPMC11855528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.