Evidence map›Paper›PMID 39997188›Full record

ArticleMarine drugs2025

Structural Characterization and Anticoagulant Potential of

Xuedong Zhang, Guangwei Yan, Xinming Liu, Jiewen Fu, Xiang Shi, Pei Cao, Yuqian Sun, Shengping Zhong, Jiale Nong, Peiqi Jiang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xuedong ZhangGuangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.
Guangwei YanCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China.
Xinming LiuGuangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.
Jiewen FuGuangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.
Xiang ShiGuangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.
Pei CaoGuangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.ORCID 0000-0002-2298-4667
Yuqian SunInstrumentation and Service Center for Molecular Sciences, Westlake University, Hangzhou 310024, China.
Shengping ZhongGuangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.
Jiale NongGuangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.
Peiqi JiangGuangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.
Yonghong LiuGuangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.ORCID 0000-0001-8327-3108
Baoshun ZhangCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China.
Qingxia YuanGuangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.ORCID 0000-0001-8023-3944
Longyan ZhaoGuangxi Key Laboratory of Marine Drugs, Institute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning 530200, China.

Funding

Innovation and Entrepreneurship Training Program for College Students 202310600026National Natural Science Foundation of China 32160220National Natural Science Foundation of China 82373788Natural Science Foundation of Guangxi Zhuang Autonomous Region 2020GXNSFFA297005Specific Research Project of Guangxi for Research Bases and Talents AD21159002
6 · The paper itself

Abstract

The depolymerized products and oligosaccharide fractions from sea cucumber fucosylated glycosaminoglycans (FGs) are promising anticoagulant candidates, and more novel FG-derived oligosaccharides from low-priced sea cucumbers are expected to be obtained. This study isolated 5-12 oligomers (OF1-OF3) with unusual branches from β-eliminative depolymerized products of

Indexed as

AnticoagulantsGlycosaminoglycansSea CucumbersAnimalsBlood CoagulationHumansOligosaccharidesAnticoagulantsGlycosaminoglycansOligosaccharidesanticoagulant activitychemical structurefucosylated glycosaminoglycanoligosaccharidessea cucumber

Identifiers

PMID39997188
PMCPMC11857587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.