ArticleBiomimetics (Basel, Switzerland)2025
AI-Optimized Lattice Structures for Biomechanics Scaffold Design.
Article in Biomimetics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed.
- Advances in 3D Printed Bone Implants: Smart Responsive Antibacterial Strategies and AI-Driven Design.Biomimetics (Basel, Switzerland) · 2026Review
- Role of polymeric nanocomposite for tissue engineering applications.RSC advances · 2026Review
- Next-generation craniomaxillofacial implants for reconstructive surgery: balancing biomechanics, biocompatibility, and bioactivity.International journal of oral science · 2026Review
- Integrated strategies in meniscus tissue engineering: from biomaterials to stem cell-driven regeneration.Frontiers in bioengineering and biotechnology · 2026Review
- Biomaterial strategies for precision regeneration of the tooth extraction socket: integrating site phenotype, pathological microenvironment, and healing sequence.Frontiers in bioengineering and biotechnology · 2026Review
- CRISPR and Artificial Intelligence in Neuroregeneration: Closed-Loop Strategies for Precision Medicine, Spinal Cord Repair, and Adaptive Neuro-Oncology.International journal of molecular sciences · 2025Review
- Application and optimization of bioengineering strategies in facilitating tendon-bone healing.Biomedical engineering online · 2025Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This research paper explores the development of AI-optimized lattice structures for biomechanics scaffold design, aiming to enhance bone implant functionality by utilizing advanced human-AI systems. The primary objective is to create scaffold structures that mimic the mechanical properties of natural bone and improve bioactivity and biocompatibility, adapting to patient-specific needs. We employed polylactic acid (PLA), calcium hydroxyapatite (cHAP), and reduced graphene oxide (rGO) as base materials, leveraging their synergistic properties. The scaffolds were intricately designed using nTopology software (nTop 5.12) and fabricated via 3D printing techniques, optimizing for biomechanical load-bearing and cellular integration. The study's findings highlight a notable enhancement in the mechanical properties of the scaffolds, with the Gyroid lattice design demonstrating a 20% higher energy-absorption capacity than traditional designs. Thermal and chemical analysis revealed a 15% increase in the thermal stability of the composites, enhancing their resilience under physiological conditions. However, the research identified minor inconsistencies in filament diameter during 3D printing, which could affect scaffold uniformity. These findings underscore the potential of integrating AI-driven design with advanced material composites in revolutionizing orthopedic implant technologies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.