Evidence map›Paper›PMID 39997048›Full record

ReviewDiseases (Basel, Switzerland)2025

The Critical Role of Penicillin in Syphilis Treatment and Emerging Resistance Challenges.

Arun Kumar Jaiswal, Lucas Gabriel Rodrigues Gomes, Aline Ferreira Maciel de Oliveira, Siomar de Castro Soares, Vasco Azevedo

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Diseases (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Frontiers in immunology · 2026
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Arun Kumar JaiswalLaboratory of Cellular and Molecular Genetics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil.ORCID 0000-0002-0558-483X
Lucas Gabriel Rodrigues GomesLaboratory of Cellular and Molecular Genetics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil.
Aline Ferreira Maciel de OliveiraLaboratory of Cellular and Molecular Genetics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil.
Siomar de Castro SoaresLaboratory of Bioinformatics, Department of Microbiology, Immunology and Parasitology, Institute of Biological and Natural Sciences, Federal University of the Triângulo Mineiro, Uberaba 38025-180, MG, Brazil.ORCID 0000-0001-7299-3724
Vasco AzevedoLaboratory of Cellular and Molecular Genetics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil.ORCID 0000-0002-4775-2280

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Syphilis, a global healthcare burden, is a sexually transmitted infection caused by the spirochete

Indexed as

antimicrobial resistancepenicillinsyphilisTreponema pallidum

Identifiers

PMID39997048
PMCPMC11854480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.