Evidence map›Paper›PMID 39997000›Full record

ArticleBiosensors2025

Radiomics-Driven CBCT Texture Analysis as a Novel Biosensor for Quantifying Periapical Bone Healing: A Comparative Study of Intracanal Medications.

Diana Lorena Garcia Lopes, Sérgio Lúcio Pereira de Castro Lopes, Daniela Maria de Toledo Ungaro, Ana Paula Martins Gomes, Nicole Berton de Moura, Bianca Costa Gonçalves, Andre Luiz Ferreira Costa

Abstract readComparative Study
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Diana Lorena Garcia LopesPostgraduate Program in Dentistry, Dentomaxillofacial Radiology and Imaging Laboratory, Department of Dentistry, Cruzeiro do Sul University (UNICSUL), São Paulo 01506-000, SP, Brazil.ORCID 0000-0002-5646-0992
Sérgio Lúcio Pereira de Castro LopesDepartment of Diagnosis and Surgery, São José dos Campos School of Dentistry, São Paulo State University (UNESP), São José dos Campos 12245-000, SP, Brazil.
Daniela Maria de Toledo UngaroDepartment of Restorative Dentistry, Institute of Science and Technology, São Paulo State University (UNESP), São José dos Campos 12245-000, SP, Brazil.
Ana Paula Martins GomesDepartment of Restorative Dentistry, Institute of Science and Technology, São Paulo State University (UNESP), São José dos Campos 12245-000, SP, Brazil.
Nicole Berton de MouraDepartment of Diagnosis and Surgery, São José dos Campos School of Dentistry, São Paulo State University (UNESP), São José dos Campos 12245-000, SP, Brazil.
Bianca Costa GonçalvesDepartment of Diagnosis and Surgery, São José dos Campos School of Dentistry, São Paulo State University (UNESP), São José dos Campos 12245-000, SP, Brazil.
Andre Luiz Ferreira CostaPostgraduate Program in Dentistry, Dentomaxillofacial Radiology and Imaging Laboratory, Department of Dentistry, Cruzeiro do Sul University (UNICSUL), São Paulo 01506-000, SP, Brazil.ORCID 0000-0003-4856-5417

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

This study aimed to evaluate the effectiveness of two intracanal medications in promoting periapical bone healing following endodontic treatment using radiomics-enabled texture analysis of cone-beam computed tomography (CBCT) images as a novel biosensing technique. By quantifying tissue changes through advanced image analysis, this approach seeks to enhance the monitoring and assessment of endodontic treatment outcomes. Thirty-four single-rooted teeth with pulp necrosis and periapical lesions were allocated to two groups (17 each): calcium hydroxide +2% chlorhexidine gel (CHX) and Ultracal XS

Indexed as

Biosensing TechniquesCone-Beam Computed TomographyCalcium HydroxideChlorhexidineHumansRadiomicsWound HealingCalcium HydroxideChlorhexidinebiomarkersdiagnostic imagingimage processingperiapical periodontitisradiomics

Identifiers

PMID39997000
PMCPMC11852422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.