Evidence map›Paper›PMID 39996979›Full record

ArticleBiosensors2025

Enzyme Biosensor Based on 3D-Printed Flow-Through Reactor Modified with Thiacalixarene-Functionalized Oligo (Lactic Acids).

Dmitry Stoikov, Dominika Kappo, Alexey Ivanov, Vladimir Gorbachuk, Olga Mostovaya, Pavel Padnya, Ivan Stoikov, Gennady Evtugyn

Abstract read
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In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dmitry StoikovAlexander Butlerov Institute of Chemistry, Kazan Federal University, 18 Kremlevskaya Street, Kazan 420008, Russia.ORCID 0000-0002-2962-5624
Dominika KappoAlexander Butlerov Institute of Chemistry, Kazan Federal University, 18 Kremlevskaya Street, Kazan 420008, Russia.ORCID 0000-0001-7294-9432
Alexey IvanovAlexander Butlerov Institute of Chemistry, Kazan Federal University, 18 Kremlevskaya Street, Kazan 420008, Russia.ORCID 0000-0002-8406-1171
Vladimir GorbachukAlexander Butlerov Institute of Chemistry, Kazan Federal University, 18 Kremlevskaya Street, Kazan 420008, Russia.
Olga MostovayaAlexander Butlerov Institute of Chemistry, Kazan Federal University, 18 Kremlevskaya Street, Kazan 420008, Russia.
Pavel PadnyaAlexander Butlerov Institute of Chemistry, Kazan Federal University, 18 Kremlevskaya Street, Kazan 420008, Russia.ORCID 0000-0002-1924-8028
Ivan StoikovAlexander Butlerov Institute of Chemistry, Kazan Federal University, 18 Kremlevskaya Street, Kazan 420008, Russia.ORCID 0000-0002-3019-7866
Gennady EvtugynAlexander Butlerov Institute of Chemistry, Kazan Federal University, 18 Kremlevskaya Street, Kazan 420008, Russia.ORCID 0000-0002-4694-7836

Funding

Russian Science Foundation 23-73-01083
6 · The paper itself

Abstract

Electrochemical enzyme biosensors are extensively utilized in clinical analysis and environmental monitoring, yet achieving effective enzyme immobilization while maintaining high activity remains a challenge. In this work, we developed a flow-through enzyme biosensor system using a 3D-printed flow-through electrochemical cell fabricated from commercially available poly (lactic acid). After modification with thiacalixarene-functionalized oligo (lactic acids) (OLAs), the material enabled efficient immobilization of uricase on the inner surface of a replaceable reactor of the cell. Swelling and hydrolytic stability of OLAs in

Indexed as

Biosensing TechniquesPrinting, Three-DimensionalElectrochemical TechniquesElectrodesEnzymes, ImmobilizedHumansUrate OxidaseUric AcidEnzymes, ImmobilizedUrate OxidaseUric Acidchronoamperometryelectrochemical biosensorflow-through analysisreplaceable reactorthiacalixarene-functionalized oligo (lactic acids)uricase

Identifiers

PMID39996979
PMCPMC11852404

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.