Evidence map›Paper›PMID 39996970›Full record

ReviewBiosensors2025

Beyond Traditional Lateral Flow Assays: Enhancing Performance Through Multianalytical Strategies.

Eleni Lamprou, Panagiota M Kalligosfyri, Despina P Kalogianni

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eleni LamprouDepartment of Chemistry, University of Patras, Rio, GR26504 Patras, Greece.ORCID 0000-0002-5179-3018
Panagiota M KalligosfyriDepartment of Chemistry, University of Patras, Rio, GR26504 Patras, Greece.
Despina P KalogianniDepartment of Chemistry, University of Patras, Rio, GR26504 Patras, Greece.ORCID 0000-0001-9638-8713

Funding

Hellenic Foundation for Research and Innovation 9098
6 · The paper itself

Abstract

Multiplex lateral flow assays are one of the greatest advancements in the world of rapid diagnostics, achieving the performance of several tests in one. These tests meet the basic requirements of increasing ease of use, low detection limit, and high specificity, as they combine the use of novel strategies, such as the exploitation of multiple detection labels, and a variety of amplification methods. These tests have proven their usefulness in many different areas, including clinical diagnostics, food, and environmental monitoring. In this review paper, we attempt to highlight and discuss the predominant changes in multianalyte LFAs, as related to their principle, their development, and their combination with other methods. Attention is paid to their flexibility and the challenges associated with the use of LFA arrays, including strategies to improve the detectability, sensitivity, and reliability of the assays. Therefore, this review emphasizes the current advances in the field to underline the possible impact of multiplex LFAs on the future of diagnostics and analytical sciences.

Indexed as

Biosensing TechniquesEnvironmental MonitoringHumansImmunoassaybiosensorimmunoassaymultiplexnanoparticlesnucleic acidspoint-of-care testingrapid testsensorstripvisual detection

Identifiers

PMID39996970
PMCPMC11853705

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.