Evidence map›Paper›PMID 39996967›Full record

ArticleBiosensors2025

A Time-Resolved Fluorescent Microsphere Immunochromatographic Assay for Determination of Vitamin B12 in Infant Formula Milk Powder.

Qianqian Lu, Yongwei Feng, Qi Zhou, Ting Yang, Hua Kuang, Chuanlai Xu, Lingling Guo

Abstract read
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Functional characterization of vitamin BFrontiers in microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qianqian LuWuxi Food Safety Inspection and Test Center, Wuxi 214142, China.
Yongwei FengWuxi Food Safety Inspection and Test Center, Wuxi 214142, China.
Qi ZhouWuxi Food Safety Inspection and Test Center, Wuxi 214142, China.
Ting YangWuxi Food Safety Inspection and Test Center, Wuxi 214142, China.
Hua KuangInternational Joint Research Laboratory for Biointerface and Biodetection, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Chuanlai XuInternational Joint Research Laboratory for Biointerface and Biodetection, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Lingling GuoInternational Joint Research Laboratory for Biointerface and Biodetection, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.ORCID 0000-0003-1930-7814

Funding

National Key R&D Program 2022YFA1207300National Natural Science Foundation of China 22236002, 92156003, 21925402Science and Technology Project of the State Administration for Market Regulation 2022MK043
6 · The paper itself

Abstract

Vitamin B12 (VB12) is an important nutrient, and its quality control in food is crucial. In this study, based on the principle of specific recognition of target analyte by monoclonal antibodies (mAbs), a time-resolved fluorescent microsphere immunochromatographic assay (TRFM-ICA) was developed to detect the content of VB12 in infant formula milk powder. First, the performance of the anti-VB12 mAb was evaluated, revealing a half-maximal inhibitory concentration of 0.370 ng/mL, an affinity constant of 2.604 × 10

Indexed as

Chromatography, AffinityInfant FormulaVitamin B 12Antibodies, MonoclonalHumansImmunoassayInfantLimit of DetectionMicrospheresPowdersAntibodies, MonoclonalPowdersVitamin B 12immunochromatographic assayinfant formula milk powdermonoclonal antibodyvitamin B12

Identifiers

PMID39996967
PMCPMC11853230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.