Evidence map›Paper›PMID 39996831›Full record

ArticleCurrent issues in molecular biology2025

The Derivative Difluoroboranyl-Fluoroquinolone "7a" Generates Effective Inhibition Against the

L Angel Veyna-Hurtado, Hiram Hernández-López, Fuensanta Del Rocío Reyes-Escobedo, Denisse de Loera, Salvador García-Cruz, Lorena Troncoso-Vázquez, Marisol Galván-Valencia, Julio E Castañeda-Delgado, Alberto Rafael Cervantes-Villagrana

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

L Angel Veyna-HurtadoDoctorado en Ciencias Farmacobiológicas, Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78210, Mexico.ORCID 0000-0003-0002-4419
Hiram Hernández-LópezLaboratorio de Investigación en Síntesis Orgánica y Modificación Química, Unidad Académica de Ciencias Químicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.
Fuensanta Del Rocío Reyes-EscobedoLaboratorio de Microbiología Sanitaria de Investigación y Servicio al Público, Unidad Académica de Ciencias Químicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.ORCID 0000-0002-4052-746X
Denisse de LoeraFacultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78210, Mexico.ORCID 0000-0002-5291-2197
Salvador García-CruzLaboratorio de Cirugía, Unidad Académica de Medicina Humana, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.ORCID 0009-0006-9233-5378
Lorena Troncoso-VázquezDepartamento de Patología, Instituto Mexicano del Seguro Social (IMSS), Zacatecas 98160, Mexico.
Marisol Galván-ValenciaLaboratorio de Investigación en Patología y Productos Naturales, Unidad Académica de Ciencias Químicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.ORCID 0000-0002-3640-5443
Julio E Castañeda-DelgadoInvestigador por México/Cátedras CONAHCYT (SECIHTI), Unidad de Investigación Biomédica de Zacatecas, Instituto Mexicano del Seguro Social (IMSS), Zacatecas 98160, Mexico.
Alberto Rafael Cervantes-VillagranaLaboratorio de Investigación en Terapéutica Experimental, Unidad Académica de Ciencias Químicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.ORCID 0000-0001-7344-353X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last decades, most bacterial strains have become increasingly resistant to antibiotics. This led the WHO to declare a global emergency in 2017 and urge the development of new active compounds. Some families of antibiotics still show high antibacterial efficacy, as is the case of fluoroquinolones, which have a broad spectrum of action. For this reason, our research group derived several compounds from fluoroquinolones, selecting a compound with good antibacterial activity for further evaluations, a difluoroboranil-fluoroquinolone complex labeled

Indexed as

antimicrobialfluoroquinolonehistopathologymolecular dockingpneumoniaS. aureus

Identifiers

PMID39996831
PMCPMC11854692

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.