Evidence map›Paper›PMID 39996826›Full record

ArticleCurrent issues in molecular biology2025

Study on the Effects and Mechanism of Corilagin on A2780 Cell Apoptosis.

Ziyang Xu, Yuhan Jiang, Tiantian Shan, Lei Hu, Minrui Wu, Hanxu Ji, Longjie Li, Yang Yi, Hongxun Wang, Limei Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ziyang XuCollege of Life Science and Technology, Wuhan Polytechnic University, Wuhan 430023, China.
Yuhan JiangCollege of Life and Science, Huazhong University of Science and Technology, Wuhan 430023, China.
Tiantian ShanCollege of Life Science and Technology, Wuhan Polytechnic University, Wuhan 430023, China.
Lei HuCollege of Life Science and Technology, Wuhan Polytechnic University, Wuhan 430023, China.
Minrui WuCollege of Life Science and Technology, Wuhan Polytechnic University, Wuhan 430023, China.
Hanxu JiCollege of Life Science and Technology, Wuhan Polytechnic University, Wuhan 430023, China.
Longjie LiCollege of Life Science and Technology, Wuhan Polytechnic University, Wuhan 430023, China.
Yang YiCollege of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, China.ORCID 0000-0001-7196-7153
Hongxun WangCollege of Life Science and Technology, Wuhan Polytechnic University, Wuhan 430023, China.
Limei WangCollege of Life Science and Technology, Wuhan Polytechnic University, Wuhan 430023, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have demonstrated corilagin's inhibitory effects on the growth of various cancer cells. Given the limited research on corilagin's impact on ovarian cancer, a particularly deadly gynecological malignancy, this study aimed to investigate corilagin's influence on A2780 ovarian cancer cell apoptosis and its underlying mechanisms. The goal was to evaluate corilagin's potential as a therapeutic agent for ovarian cancer. The results of the CCK-8 assay showed that corilagin inhibited the proliferation of A2780 ovarian cancer cells while exhibiting lower toxicity to normal ovarian surface epithelial cells (IOSE-80). We found that corilagin significantly altered the A2780 cell cycle, decreasing the proportion of cells in the G

Indexed as

apoptosiscorilaginmechanismovarian cancerp53 signaling pathway

Identifiers

PMID39996826
PMCPMC11854497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.