Evidence map›Paper›PMID 39996746›Full record

ArticleCells2025

Mesenchymal Stem/Stromal Cells (MSCs) from Mouse Pelvic vs. Long Bones Exhibit Disparate Critical Quality Attributes: Implications for Translational Studies.

Siddaraju V Boregowda, Cori N Booker, Jacqueline Strivelli, Donald G Phinney

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. PKM2Bioactive materials · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Siddaraju V BoregowdaDepartment of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458, USA.
Cori N BookerDepartment of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458, USA.ORCID 0000-0002-5274-9174
Jacqueline StrivelliDepartment of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458, USA.
Donald G PhinneyDepartment of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458, USA.ORCID 0000-0002-8688-2619

Funding

A Clinical Indications Prediction (CLIP) Scale for Human Mesenchymal Stem CellsR01HL144089 · NHLBI · UNIVERSITY OF FLORIDA · PI Donald G Phinney · 2018 to 2026
$5.4M
Species-specific and Systems Biology Approach to MSC-based TherapiesR24OD018254 · OD · SCRIPPS FLORIDA · PI PHINNEY, DONALD G · 2014 to 2017
$2.6M
NHLBI NIH HHS R01 HL144089NIH HHS OD018254 and HL144089NIH HHS R24 OD018254
6 · The paper itself

Abstract

Mesenchymal stem/stromal cells (MSCs) have been exploited as an experimental cell therapy in a broad array of clinical applications but have underperformed based on results from pre-clinical studies due to gaps in translating pre-clinical findings to human patients. Herein, we isolated mouse MSCs from pelvic bone marrow (BM

Indexed as

Bone and BonesMesenchymal Stem CellsPelvisTranslational Research, BiomedicalAnimalsBone Marrow CellsCell DifferentiationCell ProliferationHumansMiceMice, Inbred C57BLNitric Oxide Synthase Type IINitric Oxide Synthase Type IIbone marrowcell proliferationcritical quality attributesimmune suppressionmesenchymal stem cellsstromal cells

Identifiers

PMID39996746
PMCPMC11853496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.