Evidence map›Paper›PMID 39996660›Full record

ArticleGels (Basel, Switzerland)2025

Amidated and Aminated PMSSO-Hydrogels as a Promising Enzyme-Sensitive Vehicle for Antianemic Drugs.

Polina Orlova, Ivan Meshkov, Sergei Sharikov, Vsevolod Frolov, Anna Skuredina, Pavel Markov, Zoya Bobyleva, Grigorii Lakienko, Egor Latipov, Ilya Kolmogorov and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Polina OrlovaDepartment of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.
Ivan MeshkovEnikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences (ISPM RAS), Moscow 117393, Russia.ORCID 0000-0002-9169-6538
Sergei SharikovDepartment of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.ORCID 0009-0004-7643-4048
Vsevolod FrolovDepartment of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.
Anna SkuredinaDepartment of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.ORCID 0000-0003-0201-5495
Pavel MarkovDepartment of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.
Zoya BobylevaDepartment of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.ORCID 0000-0003-2450-2139
Grigorii LakienkoDepartment of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.ORCID 0000-0002-0259-1129
Egor LatipovInstitute of Nanotechnology of Microelectronics, Russian Academy of Sciences (INM RAS), Moscow 119334, Russia.ORCID 0000-0002-6809-1952
Ilya KolmogorovDepartment of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.
Sergey VasilievFederal Research Center of Problems of Chemical Physics and Medicinal Chemistry RAS (FRC PCP MC RAS), Moscow 142432, Russia.ORCID 0000-0003-0263-3007
Alexandra KalininaEnikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences (ISPM RAS), Moscow 117393, Russia.ORCID 0000-0003-2486-3276
Aziz MuzafarovEnikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences (ISPM RAS), Moscow 117393, Russia.ORCID 0000-0002-3050-3253
Irina Le-DeygenDepartment of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.ORCID 0000-0002-6366-4491

Funding

Russian Science Foundation 24-73-00091
6 · The paper itself

Abstract

In this study, we report the synthesis and characterization of aminated poly(methyl silsesquioxane)-based hydrogels ((AP/MS)SO-hydrogels) as potential enzyme-sensitive vehicles for antianemic drugs. The hydrogels were synthesized via sol-gel polymerization and functionalized with amine groups. Characterization techniques included Congo red assay, Brunauer-Emmett-Teller (BET) surface area analysis, scanning electron microscopy, elemental analysis,

Indexed as

anemiacyclodextrindrug deliveryhydrogelspolymethylsilsesquioxane

Identifiers

PMID39996660
PMCPMC11854879

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.