ArticleESC heart failure2025
In heart failure, echocardiographic parameters of right ventricular function are powerful tools to predict renal failure.
Article in ESC heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Combined podocyte, fibrotic and echocardiographic correlates of an operationally defined subclinical cardiorenal phenotype in chronic kidney disease: an exploratory study.Renal failure · 2026Observational
- Strain imaging in heart failure: from early detection to prognostic assessment.ESC heart failure · 2026Review
- Left atrioventricular coupling index by 2D and 3D echocardiography: association with exercise capacity in chronic kidney disease.Quantitative imaging in medicine and surgery · 2026Article
- Haemodynamic consequences of acute pulmonary embolism predict risk of CTPA-related acute kidney injury.ESC heart failure · 2025Article
- In heart failure, echocardiographic parameters of right ventricular function are powerful tools to predict renal failure.ESC heart failure · 2025Article
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8 authors.
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Abstract
backgroundChronic kidney disease (CKD) has a high prevalence in patients with heart failure (HF) and is associated with prolonged hospitalization, increased need for intensive care and mortality. There is an urgent need to identify factors that influence the interaction between heart and kidney disorders, often described as cardiorenal syndrome (CRS). We investigated the epidemiology and risk factors of renal insufficiency in patients with HF.
methodsWe conducted a retrospective cohort study including 281 consecutive patients with HF that are examined at regular intervals at our outpatient clinic for HF. CKD was defined as the presence of an estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m
resultsRight ventricular dysfunction was associated with CKD and WRF. In particular, echocardiographic parameters 'tricuspid annular plane systolic excursion (TAPSE) < 15 mm' (P < 0.001; OR 2.932), 'tricuspid regurgitation (TR) > I°' [P < 0.001; odds ratio (OR) 5.958] and dilatation of inferior vena cava (IVC) (P < 0.001; OR 3.670) were significantly correlated with renal failure. N-terminal pro-B-type natriuretic peptide levels were significantly associated with CKD (P < 0.001; OR 6.109) and correlated with pressure and volume load of the right heart.
conclusionsThe results of this work support the theory of right-sided cardiac backward failure, often accompanied by hypervolaemia, as a leading cause of HF-related renal failure. Right heart parameters, especially TR, TAPSE and IVC, are obtained easily by transthoracic echocardiography and can predict renal failure.
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