Evidence map›Paper›PMID 39996454›Full record

ArticleJournal of the American Chemical Society2025

Dynamic

Jonathan Farhi, Benjamin Emenike, Richard S Lee, Kirti Sad, Dorelle V Fawwal, Christian M Beusch, Robert B Jones, Ashish K Verma, Celina Y Jones, Maryam Foroozani and 9 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Jonathan FarhiDepartment of Radiation Oncology, Winship Cancer Institute of Emory University School of Medicine, Atlanta, Georgia 30322, United States.
Benjamin EmenikeDepartment of Chemistry, Emory University, Atlanta, Georgia 30322, United States.
Richard S LeeDepartment of Radiation Oncology, Winship Cancer Institute of Emory University School of Medicine, Atlanta, Georgia 30322, United States.
Kirti SadDepartment of Radiation Oncology, Winship Cancer Institute of Emory University School of Medicine, Atlanta, Georgia 30322, United States.
Dorelle V FawwalBiochemistry, Cell, and Developmental Biology Program, Emory University, Atlanta, Georgia 30322, United States.
Christian M BeuschDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, United States.
Robert B JonesDepartment of Radiation Oncology, Winship Cancer Institute of Emory University School of Medicine, Atlanta, Georgia 30322, United States.
Ashish K VermaDepartment of Chemistry, Emory University, Atlanta, Georgia 30322, United States.
Celina Y JonesDepartment of Biology, Emory College of Arts and Sciences, Atlanta, Georgia 30322, United States.
Maryam ForoozaniDepartment of Biology, Emory College of Arts and Sciences, Atlanta, Georgia 30322, United States.
Monica ReevesDepartment of Cell Biology, Emory University, Atlanta, Georgia 30322, United States.ORCID 0000-0002-6222-4865
Kiran K ParwaniDepartment of Radiation Oncology, Winship Cancer Institute of Emory University School of Medicine, Atlanta, Georgia 30322, United States.
Pritha BagchiEmory Integrated Proteomics Core, Emory University, Atlanta, Georgia 30322, United States.
Roger B DealDepartment of Biology, Emory College of Arts and Sciences, Atlanta, Georgia 30322, United States.
David J KatzDepartment of Cell Biology, Emory University, Atlanta, Georgia 30322, United States.
Anita H CorbettDepartment of Biology, Emory College of Arts and Sciences, Atlanta, Georgia 30322, United States.
David E GordonDepartment of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, United States.
Monika RajDepartment of Chemistry, Emory University, Atlanta, Georgia 30322, United States.ORCID 0000-0001-9636-2222
Jennifer M SpangleDepartment of Radiation Oncology, Winship Cancer Institute of Emory University School of Medicine, Atlanta, Georgia 30322, United States.ORCID 0000-0002-0181-3244

Funding

Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Ragini Reiney Kudchadkar · 2009 to 2026
$47.5M
IRACDA Fellowships in Research and Science Training (FIRST)K12GM000680 · NIGMS · EMORY UNIVERSITY · PI BROWN, LOU ANN S, MCCARTY, NAEL A · 2000 to 2024
$41.2M
PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM008490 · NIGMS · EMORY UNIVERSITY · PI BOSS, JEREMY M. · 1993 to 2022
$8.0M
Training Program in Biochemistry, Cell and Molecular BiologyT32GM135060 · NIGMS · EMORY UNIVERSITY · PI Lawrence H. Boise, ANITA H. CORBETT · 2020 to 2026
$2.8M
Molecular Imaging Agents for Monitoring Lysine Demethylases in CellsR35GM133719 · NIGMS · EMORY UNIVERSITY · PI RAJ, MONIKA · 2019 to 2023
$2.1M
Role of novel histone modifications and variants in transcriptional regulationR35GM150587 · NIGMS · EMORY UNIVERSITY · PI Jennifer Marie Spangle · 2023 to 2026
$1.5M
Biological Discovery through Chemical Innovation Training Program at Emory UniversityT32GM152344 · NIGMS · EMORY UNIVERSITY · PI Simon B. Blakey, ELLEN J. HESS · 2024 to 2026
$976k
NCI NIH HHS P30 CA138292NIGMS NIH HHS K12 GM000680NIGMS NIH HHS R35 GM133719NIGMS NIH HHS R35 GM150587NIGMS NIH HHS T32 GM008490NIGMS NIH HHS T32 GM135060NIGMS NIH HHS T32 GM152344
6 · The paper itself

Abstract

Dynamic protein post-translational methylation is essential for cellular function, highlighted by the essential role of methylation in transcriptional regulation and its aberrant dysregulation in diseases, including cancer. This underscores the importance of cataloging the cellular methylproteome. However, comprehensive analysis of the methylproteome remains elusive due to limitations in current enrichment and analysis pipelines. Here, we employ an l-methionine analogue, ProSeMet, that is chemoenzymatically converted to the SAM analogue ProSeAM in cells and

Indexed as

MethionineProteomeAnimalsChromatography, LiquidHumansMethylationMiceProtein Processing, Post-TranslationalTandem Mass SpectrometryMethionineProteome

Identifiers

PMID39996454
PMCPMC11887452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.