ArticleCureus2025
Utilization of Peripherally Inserted Central Catheters in Neonates Within the Neonatal Intensive Care Unit: A Decadal Single-Center Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Complications and risk factors of neonatal peripherally inserted central catheters lines.BMC pediatrics · 2026Article
- Incidence and risk factors for peripheral intravenous catheter failure in Japanese neonatal intensive care units and growing care units: a multicenter observational study.Fujita medical journal · 2026Article
- Current status of and factors influencing difficult catheter advancement in neonatal PICC insertion: a prospective multicenter observational study.European journal of pediatrics · 2026Observational
- Article
- Development and validation of a machine learning-based risk prediction model for PICC-associated bloodstream infections in preterm infants: a retrospective multicenter study.Frontiers in pediatrics · 2026Article
- Development and validation of a nomogram for predicting unplanned PICC removal in preterm infants with gestational age <32 weeks.Frontiers in pediatrics · 2026Article
- A predictive model for catheter-related bloodstream infection in neonates with peripherally inserted central catheter.Frontiers in medicine · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of peripherally inserted central catheters (PICC) in neonates has been established for numerous years, with significant advancements and enhancements observed in PICC technology over time. The objective of this study is to investigate the application trend of PICC over a 10-year period in a single-center neonatal intensive care unit (NICU). METHODOLOGY: A retrospective analysis was conducted on the infants admitted between January 2012 and October 2021 who underwent PICC catheterization. Data pertaining to gestational age, birth weight, catheter weight, placement site, and indwelling time, as well as the occurrence of infection and complications, were collected. The data was collated, and statistical analysis was performed using IBM SPSS Statistics for Windows, Version 25.0 (Released 2017; IBM Corp., Armonk, New York, United States).
resultsOut of the 1928 enrolled infants who underwent PICC catheterization, 1033 (53.58%) were males, and 895 (46.42%) were females. On the day of placement, their mean gestational age was 30.49±0.70 weeks, and their mean weight was 1398.26±14.05 g. Over the past 10 years, the number of PICC has consistently increased. The majority of cases were due to lower and right limb catheterization, with 1749 (90.72%) lower limb cases and 1477 (76.61%) right limb cases. The duration of catheter indwelling was 19.35±0.27 days. There were 297 cases (15.40%) of catheter-related complications, which included 107 cases (5.55%) of phlebitis, 71 cases (3.68%) of catheter obstruction, and 51 cases (2.65%) of catheter-related bloodstream infection (CRBSI). The binary logistic regression analysis revealed that the catheter site (upper extremity/lower extremity) (OR=0.612; 95% CI: 0.414-0.905; p=0.014) and catheter tip position (OR=1.903; 95% CI: 1.200-3.017; p=0.006) were associated with catheter complications.
conclusionsDuring neonatal PICC catheterization in the NICU, the preferred approach is to perform venous catheterization of the lower extremities and ensure that the catheter tip remains positioned within the vena cava. This technique is associated with a reduction in catheter-related complications.
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