Evidence map›Paper›PMID 39996206›Full record

ArticleCureus2025

Significances of Collimator Angle Rotation and Different Angle Combinations in Volumetric-Modulated Arc-Based Stereotactic Radiosurgery With 5-mm Leaf-Width Multileaf Collimator for Single Brain Metastases.

Kazuhiro Ohtakara, Kojiro Suzuki

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kazuhiro OhtakaraDepartment of Radiation Oncology, Kainan Hospital Aichi Prefectural Welfare Federation of Agricultural Cooperatives, Yatomi, JPN.
Kojiro SuzukiDepartment of Radiology, Aichi Medical University, Nagakute, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose In linac-based stereotactic radiosurgery (SRS) using a multileaf collimator (MLC) for multiple brain metastases (BMs), the appropriate MLC angle rotation is useful to minimize the intervening brain dose by avoiding island blocking between the lesions localized along the direction of leaf movement. However, in some linac systems, the MLC angle cannot be rotated, or the cephalad rotation range of non-coplanar arcs (NCAs) is severely limited. In addition, the significance of MLC angle rotation has yet to be clarified in SRS for single BMs. This planning study was therefore conducted to investigate the significances of MLC angle rotations and the different angle combinations in SRS with a 5-mm leaf-width MLC for single BMs using volumetric-modulated arcs (VMA) consisting of one coplanar arc and two NCAs rotated 60º cranially. Materials and methods The study subjects were 30 lesions in 27 patients with the gross tumor volume (GTV) ranging from 0.08 cc to 48.09 cc (median 9.81 cc). Four VMA-based SRS plans were created for each GTV using an Agility

Indexed as

brain metastasescollimator angledose conformitydose gradientdose inhomogeneitymultileaf collimatornon-coplanar arcsingle brain metastasisstereotactic radiosurgeryvolumetric-modulated arc therapy

Identifiers

PMID39996206
PMCPMC11849758

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.