Evidence map›Paper›PMID 39996187›Full record

ArticleCureus2025

Safety and Efficacy of Enfortumab Vedotin in a Patient With Metastatic Urothelial Carcinoma on Dialysis: A Case Report.

Yuto Tsubonuma, Yujiro Nagata, Katsuyoshi Higashijima, Akinori Minato, Ikko Tomisaki, Naohiro Fujimoto

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuto TsubonumaUrology, University of Occupational and Environmental Health, Kitakyushu, JPN.
Yujiro NagataUrology, University of Occupational and Environmental Health, Kitakyushu, JPN.
Katsuyoshi HigashijimaUrology, University of Occupational and Environmental Health, Kitakyushu, JPN.
Akinori MinatoUrology, University of Occupational and Environmental Health, Kitakyushu, JPN.
Ikko TomisakiUrology, University of Occupational and Environmental Health, Kitakyushu, JPN.
Naohiro FujimotoUrology, University of Occupational and Environmental Health, Kitakyushu, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, enfortumab vedotin has emerged as a promising treatment option for metastatic urothelial carcinoma. Although it does not require dosage adjustments in patients with renal failure, its safety and efficacy, particularly in those undergoing dialysis, remain unclear. We report a case of metastatic urothelial carcinoma in a patient undergoing hemodialysis who achieved a complete response to enfortumab vedotin therapy without severe adverse events. This complete response was maintained for two years without any severe complications. Our case demonstrates that enfortumab vedotin can be safely administered long-term to patients undergoing hemodialysis.

Indexed as

complete responseenfortumab vedotinhemodialysismetastatic urothelial carcinomarenal failure

Identifiers

PMID39996187
PMCPMC11848219

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.