ArticleClinical epidemiology2025
The Danish Lymphoid Cancer Research (DALY-CARE) Data Resource: The Basis for Developing Data-Driven Hematology.
Article in Clinical epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Effects of chronic lymphocytic leukaemia (CLL)-directed therapy on diffuse large B-cell lymphoma (DLBCL) type Richter transformation compared to de novo DLBCL in a nationwide cohort.British journal of haematology · 2026Article
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- Rituximab maintenance after first-line rituximab-bendamustine.Blood advances · 2026Article
- CD20 negativity at the start of second-line therapy predicts a shorter overall survival in B-cell lymphomas.Blood neoplasia · 2026Article
- Hypertension affects survival and treatment in chronic lymphocytic leukemia.Blood advances · 2026Article
- Machine learning enhances risk stratification and treatment failure prediction in diffuse large B-cell lymphoma.HemaSphere · 2026Article
- Revised criteria for light chain MGUS enhance diagnostic accuracy and risk stratification.Blood cancer journal · 2026Article
- Post-treatment infection prediction in CLL using domain adaptation of lymphoma electronic health records.Acta oncologica (Stockholm, Sweden) · 2026Article
- Central nervous system involvement in CLL: an international retrospective study by ERIC, the European Research Initiative on CLL.Blood advances · 2026Article
- The Danish Lymphoid Cancer Research (DALY-CARE): Genetic Cohort Profile.Clinical epidemiology · 2026Article
- One for the ages: impact of age on international prognostic indices in lymphoid cancer.Blood advances · 2025Article
- Polypharmacy independently predicts survival, hospitalization, and infections in patients with lymphoid cancer.HemaSphere · 2025Article
- Revised free light chain reference intervals enhance risk stratification in monoclonal gammopathy of undetermined significance and reduce overdiagnosis.Blood cancer journal · 2025Article
- A Real-World International Staging System (RW-ISS) for patients with newly diagnosed multiple myeloma.Blood cancer journal · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Lymphoid-lineage cancers (LC; International Classification of Diseases, 10 Aim: Creating a large-scale data repository for patients with LC to develop data-driven hematology. Methods: We gathered electronic health data and created open-source processing pipelines to create a comprehensive data resource for Danish LC Research (DALY-CARE) approved for epidemiological, molecular, and data-driven research. Results: We included all Danish adults registered with LC diagnoses since 2002 (n=65,774) and combined 10 nationwide registers, electronic health records (EHR), and laboratory data on a high-powered cloud-computer to develop a secure research environment. Among other, data include treatments (ie 21,750 cytoreductive treatment plans, 21.3M outpatient prescriptions, and 12.7M in-hospital administrations), biochemical analyses (77.3M), comorbidity (14.8M ICD10 codes), pathology codes (4.5M), treatment procedures (8.3M), surgical procedures (1.0M), radiological examinations (3.3M), vital signs (18.3M values), and survival data. We herein describe the data infrastructure and exemplify how DALY-CARE has been used for molecular studies, real-world evidence to evaluate the efficacy of care, and mAI deployed directly into EHR systems. Conclusion: The DALY-CARE data resource allows for the development of near real-time decision-support tools and extrapolation of clinical trial results to clinical practice, thereby improving care for patients with LC while facilitating streamlining of health data infrastructure across cohorts and medical specialties.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.