Evidence map›Paper›PMID 39996137›Full record

ArticleResuscitation plus2025

Database and geospatial mapping study of those eligible for extracorporeal cardiopulmonary resuscitation in the Thames Valley Region, England.

Oscar Millerchip, Jasper Eddison, Alex Rosenberg, Jon Bailey, James Raitt

Abstract read
In one paragraph

Article in Resuscitation plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oscar MillerchipNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, Guy Scadding Building, Cale Street, London SW3 6LY, United Kingdom.
Jasper EddisonNational Heart and Lung Institute, Faculty of Medicine, Imperial College London, Guy Scadding Building, Cale Street, London SW3 6LY, United Kingdom.
Alex RosenbergHarefield Hospital, Guys' and St Thomas' NHS Foundation Trust, Hill End Road, Harefield, Uxbridge UB9 6JH, United Kingdom.
Jon BaileyThames Valley Air Ambulance, Stokenchurch House, Oxford Road, Stokenchurch, High Wycombe HP14 3SX, United Kingdom.
James RaittThames Valley Air Ambulance, Stokenchurch House, Oxford Road, Stokenchurch, High Wycombe HP14 3SX, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Out-of-hospital cardiac arrest survival remains low. Extracorporeal-cardiopulmonary resuscitation (ECPR) is a therapy for refractory out-of-hospital cardiac arrest that can improve survivability by decreasing the time a patient is without adequate perfusion, the low-flow time. Access to ECPR is limited by the number, location and delivery approach of centres offering this therapy. Aims: This study aims to identify how many patients are eligible for ECPR in the Thames Valley area and provide geographical analysis to appraise the specialist-centre approach of ECPR delivery in the region. Methods: Data from out-of-hospital cardiac arrests attended by the Thames Valley Air Ambulance from 1st Jan 2022 to 1st Jan 2024 were reviewed for eligibility to receive ECPR against inclusion criteria. Eligible cases were modelled using Geographic Information System software, and spatial autocorrelation analysis was performed to identify any significant 'hotspots', 'cold spots', or significant geographical distribution of eligible cases. Results: Of some 1,182 cardiac arrests attended, 188 (16%) cases were eligible under inclusion criteria for ECPR. In 2023 seven patients received ECPR, all focussed in a small area of the Thames Valley. The majority of eligible cases fall outside of the catchment of any one hospital when utilising the hospital-based or rendez-vous models of ECPR. Global Moran's analysis of the entire region found no significant clustering or dispersal, suggesting a near-random distribution despite some evidence of hotspots. Conclusion: ECPR can improve survival for out-of-hospital cardiac arrest, but time constraints preclude access to this therapy for many, which affects equitability across a geographical area. Geospatial analysis techniques can aid in reviewing the optimal delivery methods of ECPR and improve equitable geographical access to services. The methodology described may aid other organisations in planning the delivery of ECPR.

Indexed as

Extracorporeal cardiopulmonary resuscitationPre-hospitalRefractory cardiac arrest

Identifiers

PMID39996137
PMCPMC11848498

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.