ArticlePhysics and imaging in radiation oncology2025
Dose-volume parameter evaluation of a sub-fractionation workflow for adaptive radiotherapy of prostate cancer patients on a 1.5 T magnetic resonance imaging radiotherapy system.
Article in Physics and imaging in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Reconstructed dose and geometric coverage for tight margins using intrafraction re-planning on an integrated magnetic resonance imaging and linear accelerator system for prostate cancer patients.Physics and imaging in radiation oncology · 2025Article
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7 authors.
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Abstract
Background and purpose: This study focuses on evaluating a sub-fractionation workflow for intrafraction motion mitigation of prostate cancer patients on a 1.5 T magnetic resonance imaging radiotherapy system. Materials and methods: The investigated workflow consisted of two sub-fractions where intrafraction drift correction steps were applied based on a daily reference plan. However, the daily contours were only rigidly shifted to match the intrafraction anatomies and therefore the clinical dosimetric constraints might be violated. In this work, daily contours were deformed to match the intrafraction anatomies and the online plans were re-calculated for a total of 15 patients. The deformed prostate contours were inspected by radiation oncologists and corrections were performed when necessary. Finally, a dose-volume parameter evaluation was performed on a sub-fraction level using the clinical plan parameters. Results: Clinically acceptable coverage was reported for the target structures resulting in mean V Conclusion: Given our results on the CTV coverage we can conclude that the sub-fractionation workflow met the dosimetric constraints for the hypofractionated treatment of the analyzed group of prostate cancer patients. A future dose accumulation study can provide further insights into the suitability of the clinical margins.
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