Evidence map›Paper›PMID 39995958›Full record

ReviewInternational journal of nanomedicine2025

Mucoadhesive-to-Mucopenetrating Nanoparticles for Mucosal Drug Delivery: A Mini Review.

Bin Zheng, Dingyi Liu, Xiaowen Qin, Dahong Zhang, Pu Zhang

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
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  7. Review
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  10. Bridging bioactive metabolites ofFrontiers in pharmacology · 2026
    Review
  11. Article
  12. Article
  13. Review
  14. Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bin Zheng *Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, People's Republic of China.
Dingyi Liu *Urology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, People's Republic of China.
Xiaowen Qin *Department of Nutrition and Food Hygiene, The National Key Discipline, School of Public Health, Harbin Medical University, Harbin, 15008, People's Republic of China.
Dahong ZhangUrology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, People's Republic of China.
Pu ZhangUrology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucosal tissue acts as a barrier between the human body's internal environment and the external world. The mucosal tissue is shielded from injurious environmental chemicals, toxins, and pathogens by a mucus layer lining above the mucosal tissue, and meanwhile the periodic mucosal clearance accelerates the removal of mucoadhesive components. And therefore, transmucosal drug delivery is limited. Nanocarriers for mucosal drug delivery is recently developed to enhance either long retention of drugs within the mucus layer or rapid translocation of drugs across the mucus layer. Among all these types of drug delivery systems, mucoadhesive-to-mucopenetrating nanocarriers transport drugs most efficiently into targeted mucosal tissues. In this review, recent progress on the mucoadhesive-to-mucopenetrating drug delivery systems and their application are updated.

Indexed as

Drug Delivery SystemsMucous MembraneNanoparticle Drug Delivery SystemNanoparticlesAdhesivenessAnimalsDrug CarriersHumansMucusDrug CarriersNanoparticle Drug Delivery Systemdrug deliverymucoadhesionmucopenetrationnanoparticles

Identifiers

PMID39995958
PMCPMC11849417

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.