Evidence map›Paper›PMID 39995816›Full record

ArticleIDCases2025

Disseminated histoplasmosis and hemophagocytic lymphohistiocytosis: A case report.

Ruth C Angrand, Lauren Telesca, Muhammad Aslam

Abstract readCase Reports
In one paragraph

Article in IDCases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ruth C AngrandDepartment of Internal Medicine, Stony Brook University Hospital, Stony Brook, New York, USA.
Lauren TelescaRenaissance School of Medicine, Stony Brook University Hospital, Stony Brook, New York, USA.
Muhammad AslamDepartment of Internal Medicine, Stony Brook University Hospital, Stony Brook, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is an immune deregulatory disorder resulting in severe inflammation and potentially fatal complications involving the bone marrow, liver, or brain; HLH can be considered primary. Secondary HLH is often associated with a specific trigger, including infectious trigger that could be bacterial, viral, fungal or parasitic. Histoplasmosis-associated HLH is a relatively rare but previously reported complication. This case report presents a patient with HLH caused by disseminated histoplasmosis who was treated with etoposide, rituximab, amphotericin B, and itraconazole. This case report aims to highlight the importance of keeping a broad differential for when patients present with fevers of unknown origin.

Indexed as

Disseminated histoplasmosisHLHLymphohistiocytosis

Identifiers

PMID39995816
PMCPMC11848793

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.