ArticleQuantitative imaging in medicine and surgery2025
One-stop combined coronary-craniocervical computed tomography angiography with low-dose body coverage using artificial intelligence iterative reconstruction: a clinically feasible solution to multi-territorial atherosclerosis diagnosis.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Evaluation of gastric cancer using artificial intelligence iterative reconstruction on abdominal CT: image quality and diagnostic accuracy.Abdominal radiology (New York) · 2026Article
- Exploring the diagnostic performance of low-dose CT for colorectal cancer assessment: feasibility of artificial intelligence iterative reconstruction.Quantitative imaging in medicine and surgery · 2026Article
- Artificial intelligence iterative imaging reconstruction with low-dose CT scans for hepatic metastases.Scientific reports · 2026Article
- Low-dose corticomedullary phase CT urography with artificial intelligence iterative reconstruction for bladder cancer evaluation.The British journal of radiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Computed tomography angiography (CTA) is an effective means to detect atherosclerosis yet a whole-body scan may involve excessive dose that can only be considered in extreme cases. This study is to test the feasibility and value of adding a low-dose body CTA to the combined coronary-craniocervical CTA by using artificial intelligence iterative reconstruction (AIIR). Methods: A total of 100 patients scheduled for one-stop combined coronary-craniocervical CTA were enrolled to receive an extended CTA covering from intracranial to iliofemoral arteries, by adding a low-dose body CTA to the coronary-craniocervical CTA. Radiation dose, contrast medium volume and the resulting image quality of the added scan, reconstructed by the AIIR, were compared to those from the retrospectively collected routine-dose aortic CTA. Diagnostic findings beyond the coronary and craniocervical arteries, which would have been missed if not for the extension, and their influence on clinical management, were assessed on the low-dose images. Results: With rather low cost of radiation and contrast dosage (1.6 mSv, 25.4 mL), the body CTA with AIIR reconstruction yielded diagnostically sufficient image quality and significantly higher contrast-to-noise ratio (CNR) as compared to routine-dose aortic CTA at various vascular locations (all P<0.05). Additional atherosclerosis was detected by the added low-dose body CTA for a substantial proportion of patients (73/100, 73%). Incidental findings in the body were found in 26 patients with 44 detections. The corresponding clinical management of 38% patients was changed due to the atherosclerotic and non-atherosclerotic vascular findings on body arteries. Most of the atherosclerosis were calcified plaques (38/73, 52%) and rated as mild stenosis (62/73, 85%). The prevalence of body arterial atherosclerosis was remarkably higher among patients diagnosed with coronary-craniocervical atherosclerosis than those without coronary-craniocervical atherosclerosis (85% Conclusions: Extending the one-stop combined coronary-craniocervical CTA with low-dose body coverage as enabled by the AIIR is technically feasible and of evident clinical value in clinical decision-making, taking a concrete step towards multi-territorial atherosclerosis diagnosis and management in practical application.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.